Results 91 to 100 of about 880,221 (312)

Cloning of the wheat Yr15 resistance gene sheds light on the plant tandem kinase-pseudokinase family

Nature Communications, 2018
Yellow rust fungus severely limits global wheat production and breeding of durable resistance is challenging. Here Klymiuk et al. isolate the broad-spectrum Yr15 resistance gene from wild emmer wheat and show that it is a member of a distinct tandem ...
Valentina Klymiuk, Elitsur Yaniv, Lin Huang, Dina Raats, Andrii Fatiukha, Shisheng Chen, Lihua Feng, Zeev Frenkel, Tamar Krugman, Gabriel Lidzbarsky, Wei Chang, Marko J. Jääskeläinen, Christian Schudoma, Lars Paulin, Pia Laine, Harbans Bariana, Hanan Sela, Kamran Saleem, Chris Khadgi Sørensen, Mogens S. Hovmøller, Assaf Distelfeld, Boulos Chalhoub, Jorge Dubcovsky, Abraham B. Korol, Alan H. Schulman, Tzion Fahima   +25 more
doaj   +1 more source

The Croonian Lectures on Evolution and Dissolution of the Nervous System [PDF]

, 1884
J. H. Jackson
openalex   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Evolution of Genetic Systems [PDF]

, 1959
Curt Stern
openalex   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

Depth shapes microbiome assembly and network stability in the Mariana Trench

Microbiology Spectrum
The Mariana Trench, a stable marine ecosystem minimally impacted by human activities, has the greatest vertical depth in the ocean. Depth gradients profoundly influence the physical, chemical, and biotic conditions in the deep oceans.
Yi Li, Jinjun Kan, Feilong Liu, Kaiyue Lian, Yantao Liang, Hongbing Shao, Andrew McMinn, Hualong Wang, Min Wang   +8 more
doaj   +1 more source

LECTURES ON THE EVOLUTION OF THE FILICINEAN VASCULAR SYSTEM [PDF]

, 1907
A. G. Tansley
openalex   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Research on micro-influence mechanism of fine particles on dynamic characteristics of graded macadam materials in heavy-haul railway subgrade beds

Case Studies in Construction Materials, 2023
Fine particle content is an important physical state parameter of graded macadam materials used in heavy-haul railway subgrade beds. Understanding the micro-influence mechanism of the fine particle content on the filler’s dynamical characteristics is of ...
Zhihao Yang, Siaw Ackah Frank, Huaiping Feng, Shaohua Li   +3 more
doaj  

LECTURES ON THE EVOLUTION OF THE FILICINEAN VASCULAR SYSTEM.¹ [PDF]

, 1907
A. G. Tansley
openalex   +1 more source