Results 91 to 100 of about 27,661,028 (295)

Diversity and Ecological Roles of Deep-Sea Viruses

open access: yesOcean-Land-Atmosphere Research
The deep sea is one of the least-explored ecosystems on Earth. Deep-sea virus communities are crucial components of this ecosystem and play crucial roles in food webs and biogeochemical cycles.
Ying Han   +4 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Concept Evolution in Information System Evolution [PDF]

open access: yes, 2004
Contains fulltext : 60241.pdf (author's version ) (Open Access)
Proper, H.A., Hoppenbrouwers, S.J.B.A.
openaire  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A new Early Jurassic dinosaur represents the earliest-diverging and oldest sauropodomorph of East Asia

open access: yesScientific Reports
A new dinosaur assemblage from the Lower Jurassic at Wande Town, Wuding County, Yunnan Province, China is discovered recently. Here a new sauropodomorph from this site, Wudingloong wui gen. et sp.
Ya-Ming Wang   +8 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Vibrio cyclitrophicus phage encoding gene transfer agent fragment, representing a novel viral family

open access: yesVirus Research
Vibrio is a prevalent bacterial genus in aquatic environments and exhibits diverse metabolic capabilities, playing a vital role in marine biogeochemical cycles. This study isolated a novel virus infecting Vibrio cyclitrophicus, vB_VviC_ZQ26, from coastal
Yao Xiong   +12 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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