Results 41 to 50 of about 79,392 (261)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Early human occupation of Australia’s eastern seaboard
Scientific ReportsSecure archaeological evidence for human occupation on the eastern seaboard of Australia before ~ 25,000 years ago has proven elusive. This has prompted some researchers to argue that the coastal margins remained uninhabited prior to 25 ka.
Shaun Adams +19 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
The tectonic and volcanic evolution of the Mangatolu Triple Junction [PDF]
, 2020 <p>The Mangatolu Triple Junction (MTJ) is an intraoceanic back-arc spreading center that is host to at least 3 distinct hydrothermal systems. It is located in the NE Lau Basin, which opened due to rollback of the Pacific plate along the Tonga-Kermadec trench.
Rebecca Mensing +4 more
openaire +3 more sources
EVOLUTION AND DEVELOPMENT OF THE TRIPLE HELIX MODEL IN TURKEY
InterConf, 2021 The triple helix cooperation is in on-going development process in Turkey. Government is starting initiatives and supporting the industry and universities with various financial incentives and opportunities. Turkish and Kazakh “research universities” have a special status, and they are expected to produce knowledge that will be of great significance ...
Demet Soylu, Regina Andekina
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Anchoring zero valence single atoms of nickel and iron on graphdiyne for hydrogen evolution
Nature Communications, 2018 Single atom catalysts provide the most efficient metal atoms usage and afford active site homogeneity, but surface attachment has proven challenging. Here, the authors use triple-bond-rich graphdiyne to anchor nickel/iron atoms and show high hydrogen ...
Yurui Xue +8 more
doaj +1 more source
ORBITS, MASSES, AND EVOLUTION OF MAIN BELT TRIPLE (87) SYLVIA [PDF]
The Astronomical Journal, 2012 14 pages, 8 figures, accepted to ...
Fang, J, Margot, JL, Rojo, P
openaire +5 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Possible Formation Scenario of the Gaia BH1: Inner Binary Merger in Triple Systems
The Astrophysical Journal LettersBased on astrometric measurements and spectral analysis from Gaia DR3, two quiescent black hole (BH) binaries, Gaia BH1 and BH2, have been identified. Their origins remain controversial, particularly for Gaia BH1.
Zhuowen Li +7 more
doaj +1 more source