Results 41 to 50 of about 27,787 (252)
Multi-Player Evolutionary Game of Network Attack and Defense Based on System Dynamics
Mathematics, 2021 We formalize the adversarial process between defender and attackers as a game and study the non-cooperative evolutionary game mechanism under bounded rationality.
Pengxi Yang, Fei Gao, Hua Zhang
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Evolutionarily Stable Strategies in Sports Contests [PDF]
Journal of Sports Economics, 2011 Most articles on sports economics presume the well-known Nash equilibrium concept. In this article, however, we apply evolutionary game theory in a sports-contest model. If clubs follow evolutionarily stable strategies (ESS), then ESS generate greater investments and smaller profits than predicted by Nash’s strategies, independent of whether a club is ...
openaire +4 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Exploring Evolutionary Fitness in Biological Systems Using Machine Learning Methods
Entropy, 2020 Here, we propose a computational approach to explore evolutionary fitness in complex biological systems based on empirical data using artificial neural networks. The essence of our approach is the following.
Oleg Kuzenkov +2 more
doaj +1 more source
Evolutionary stability in the asymmetric volunteer's dilemma. [PDF]
PLoS ONE, 2014 It is often assumed that in public goods games, contributors are either strong or weak players and each individual has an equal probability of exhibiting cooperation.
Jun-Zhou He, Rui-Wu Wang, Yao-Tang Li
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Evolutionary game analysis on decision-making behaviors of participants in mega projects
Humanities & Social Sciences Communications, 2023 Mega projects have a huge impact on the economy and society. Preventing collusive behavior and introducing public participation in supervision are conducive to the governance of mega projects and are crucial to the success of mega projects.
Daoping Chen, Binbin Chen
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source