Results 71 to 80 of about 27,787 (252)
Environmental Research Letters, 2017 Drought-deciduous and evergreen species are both common in tropical forests, where there is the need to cope with water shortages during periodic dry spells and over the course of the dry season. Which phenological strategy is favored depends on the long-
Giulia Vico +4 more
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Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Journal of Physics: ComplexityHumans are bounded rational at best and this, we argue, has worked in their favor in the hunter–gatherer society where emergence of a coordinated action, leading to cooperation, is otherwise the standard stag-hunt dilemma (when individuals are rational).
Joy Das Bairagya, Sagar Chakraborty
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FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Frontiers in Public HealthIntroductionCurrently in China, there is a lack of well-defined and viable incentive mechanisms at the governmental and hospital levels to support the development of young medical talents, thereby hindering their growth Existing studies primarily ...
Si Li +6 more
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Equilibrium Distributions of Populations of Biological Species on Networks of Social Sites
Journal of Biological Dynamics, 2019 We investigate the problem of how a population of biological species would distribute over a given network of social sites so that their social contacts through the connected sites can be maximized (or minimized).
Min Wang, Wen Zhou, Zhijun Wu
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
An evolutionary game based security decision algorithm for wireless sensor networks
Journal of Measurement Science and Instrumentation, 2022 When using traditional game methods to study information security of the wireless sensor networks, players are mostly based on the assumption of completely rational.
XIA Jinzong +3 more
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