Results 41 to 50 of about 2,283,559 (289)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Parallelism and evolutionary algorithms [PDF]
This paper contains a modern vision of the parallelization techniques used for evolutionary algorithms (EAs). The work is motivated by two fundamental facts: 1) the different families of EAs have naturally converged in the last decade while parallel EAs (PEAs) are still lack of unified studies; and 2) there is a large number of improvements in these ...
Enrique Alba 0001, Marco Tomassini
openaire +1 more source
A Chaotic System with Infinite Equilibria and Its S-Box Constructing Application
Systems with many equilibrium points have attracted considerable interest recently. A chaotic system with a line equilibrium has been studied in this work. The system has infinite equilibria and exhibits coexisting chaotic attractors.
Xiong Wang +5 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Evolutionary Demographic Algorithms
4 pages and 6 ...
Marco A. R. Erra +2 more
openaire +2 more sources
This paper proposes an adaptive-based single-phase higher-order sliding mode controller (SMC) optimized by the honey badger algorithm (HBA). The developed control method is employed for load frequency control (LFC) in electrical power systems (EPSs) that
Anh-Tuan Tran +3 more
doaj +1 more source
Non-uniform cellular genetic algorithms [PDF]
In this paper, we introduce the concept of non-uniform cellular genetic algorithm, in which a number of parameters that affect the operation of genetic operators is dependent on the location of the cells of a given cellular space.
N. M. Ershov
doaj +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source

