Results 41 to 50 of about 88,043 (267)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

A Cellular Automata Models of Evolution of Transportation Networks [PDF]

open access: yesComputer Science, 2002
We present a new approach to modelling of transportation networks. Supply of resources and their influence on the evolution of the consuming environment is a princqral problem considered.
Mariusz Paszkowski, Pawel Topa
doaj  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Robust Adaptive Sliding Mode-Based Frequency Control for Nonlinear Thermal Power Systems With Boiler Dynamics

open access: yesIEEE Access
This paper proposes a robust load frequency control (LFC) strategy for nonlinear thermal power systems (TPS). Unlike conventional LFC models, the developed system explicitly incorporates governor dead band, generation rate constraint, and boiler dynamics,
Anh-Tuan Tran   +3 more
doaj   +1 more source

Seepage Analysis in Short Embankments Using Developing a Metaheuristic Method Based on Governing Equations

open access: yesApplied Sciences, 2020
Seepage is one of the most challenging issues in some procedures such as design, construction, and operation of embankment or earth fill dams. The purpose of this research is to develop a new solution based on governing equations to solve the seepage ...
Dongchun Tang   +6 more
doaj   +1 more source

EmiR: Evolutionary minimization for R

open access: yesSoftwareX, 2022
Classical minimization methods, like the steepest descent or quasi-Newton techniques, have been proved to struggle in dealing with optimization problems with a high-dimensional search space or subject to complex nonlinear constraints. In the last decade,
Davide Pagano, Lorenzo Sostero
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Load Frequency Control Based on Gray Wolf Optimizer Algorithm for Modern Power Systems

open access: yesEnergies
The increasing complexity of modern power systems (MPSs), driven by the integration of renewable energy sources and multi-area configurations, demands robust and adaptive load frequency control (LFC) strategies.
Dao Huy Tuan   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Function-based hybrid synchronization types and their coexistence in non-identical fractional-order chaotic systems

open access: yesAdvances in Difference Equations, 2018
This paper presents new results related to the coexistence of function-based hybrid synchronization types between non-identical incommensurate fractional-order systems characterized by different dimensions and orders.
Adel Ouannas   +4 more
doaj   +1 more source

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