Results 31 to 40 of about 88,043 (267)
A Chaotic System with Infinite Equilibria and Its S-Box Constructing Application
Applied Sciences, 2018 Systems with many equilibrium points have attracted considerable interest recently. A chaotic system with a line equilibrium has been studied in this work. The system has infinite equilibria and exhibits coexisting chaotic attractors.
Xiong Wang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
IEEE AccessThis paper proposes an adaptive-based single-phase higher-order sliding mode controller (SMC) optimized by the honey badger algorithm (HBA). The developed control method is employed for load frequency control (LFC) in electrical power systems (EPSs) that
Anh-Tuan Tran +3 more
doaj +1 more source
Non-uniform cellular genetic algorithms [PDF]
Компьютерные исследования и моделирование, 2015 In this paper, we introduce the concept of non-uniform cellular genetic algorithm, in which a number of parameters that affect the operation of genetic operators is dependent on the location of the cells of a given cellular space.
N. M. Ershov
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Applied Sciences, 2020 In mining and civil engineering applications, a reliable and proper analysis of ground vibration due to quarry blasting is an extremely important task. While advances in machine learning led to numerous powerful regression models, the usefulness of these
Hong Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Investigating the Applications of Machine Learning Techniques to Predict the Rock Brittleness Index
Applied Sciences, 2020 Despite the vast usage of machine learning techniques to solve engineering problems, a very limited number of studies on the rock brittleness index (BI) have used these techniques to analyze issues in this field.
Deliang Sun +6 more
doaj +1 more source