Results 111 to 120 of about 935,716 (329)

Session 5: Development, Neuroscience and Evolutionary Psychology [PDF]

open access: yes, 2002
Proceedings of the Pittsburgh Workshop in History and Philosophy of Biology, Center for Philosophy of Science, University of Pittsburgh, March 23-24 2001 Session 5: Development, Neuroscience and Evolutionary ...
Machamer, Peter   +3 more
core  

The use of information theory in evolutionary biology

open access: yes, 2011
Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a population adapts to a
Adami   +79 more
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

DNA damage repair proteins across the Tree of Life

open access: yesiScience, 2023
Summary: Genome maintenance is orchestrated by a highly regulated DNA damage response with specific DNA repair pathways. Here, we investigate the phylogenetic diversity in the recognition and repair of three well-established DNA lesions, primarily ...
Emily Nischwitz   +8 more
doaj  

Evolutionary Biology Needs Wild Microbiomes

open access: yesFrontiers in Microbiology, 2017
The microbiome is a vital component to the evolution of a host and much of what we know about the microbiome derives from studies on humans and captive animals.
Sarah M. Hird
doaj   +1 more source

The Evolution of Cell Communication: The Road not Taken. [PDF]

open access: yes, 2009
In the post-genomic era the complex problem of evolutionary biology can be tackled from the top-down, the bottom-up, or from the middle-out. Given the emergent and contingent nature of this process, we have chosen to take the latter approach, both as a ...
Rehan, VK, Torday, JS
core   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

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