Results 121 to 130 of about 389,475 (313)
iScience, 2023 Summary: TLR7 plays a crucial role in sensing viral ssRNA and initiating immune responses. Piscine TLR7 also responds to dsRNA challenge. dsRNA exists in almost all the viruses at specific stages.
Rui Jiang +4 more
doaj
Evolutionary accumulation modelling in AMR: machine learning to infer and predict evolutionary dynamics of multi-drug resistance [PDF]
arXivCan we understand and predict the evolutionary pathways by which bacteria acquire multi-drug resistance (MDR)? These questions have substantial potential impact in basic biology and in applied approaches to address the global health challenge of antimicrobial resistance (AMR).
arxiv
Evolutionary Biology. Volume I. T
, 1968 John Buettner‐Janusch
openalex +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
iScience, 2023 Summary: Light organs (LO) with symbiotic bioluminescent bacteria are hallmarks of many bobtail squid species. These organs possess structural and functional features to modulate light, analogous to those found in coleoid eyes.
Lisa Rouressol +8 more
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Evaluating the dissemination of evolutionary biology concepts in medicine. [PDF]
Braz J Med Biol Res, 2023 Mermelstein C, Costa ML, Coutinho CC.
europepmc +1 more source
Comparative Analysis of the Saccharomyces cerevisiae and Caenorhabditis elegans Protein Interaction Network [PDF]
BMC Evolutionary Biology 2005, 5:23, 2005 Protein interaction networks aim to summarize the complex interplay of proteins in an organism. Early studies suggested that the position of a protein in the network determines its evolutionary rate but there has been considerable disagreement as to what extent other factors, such as protein abundance, modify this reported dependence.
arxiv
Molecular Oncology, EarlyView.This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain +3 more
wiley +1 more source
DNA damage repair proteins across the Tree of Life
iScience, 2023 Summary: Genome maintenance is orchestrated by a highly regulated DNA damage response with specific DNA repair pathways. Here, we investigate the phylogenetic diversity in the recognition and repair of three well-established DNA lesions, primarily ...
Emily Nischwitz +8 more
doaj