Results 131 to 140 of about 389,475 (313)

SECOND INTERNATIONAL CONGRESS OF SYSTEMATIC AND EVOLUTIONARY BIOLOGY [PDF]

, 1978

openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Extensive intragenomic variation in the internal transcribed spacer region of fungi

iScience, 2023
Summary: Fungi are among the most biodiverse organisms in the world. Accurate species identification is imperative for studies on fungal ecology and evolution.
Michael J. Bradshaw, M. Catherine Aime, Antonis Rokas, Autumn Maust, Swarnalatha Moparthi, Keila Jellings, Alexander M. Pane, Dylan Hendricks, Binod Pandey, Yuanning Li, Donald H. Pfister   +10 more
doaj  

Evolutionary System Biology

, 2021
Peer ...
Valverde, Sergi, Ares, Saúl, Balsa-Canto, Eva, Banga, Julio R., Elena, Santiago F., Iranzo, Jaime, Manrubia Cuevas, Susanna   +6 more
openaire   +1 more source

MIF as an oncogenic driver of low‐heterogeneity melanomas

Molecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran, Gabriela Athziri Sánchez‐Zuno, Rajan P. Kulkarni, Harriet M. Kluger, Richard Bucala   +4 more
wiley   +1 more source

Single-cell phenotypic plasticity modulates social behavior in Dictyostelium discoideum

iScience, 2023
Summary: In Dictyostelium chimeras, “cheaters” are strains that positively bias their contribution to the pool of spores, i.e., the reproductive cells resulting from development.
Mathieu Forget, Sandrine Adiba, Silvia De Monte   +2 more
doaj  

Films, Filmstrips and Videotapes in Evolutionary Biology [PDF]

, 1984
Nathan H. Hart
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

A family of crown-of-thorns starfish spine-secreted proteins modify adult conspecific behavior

iScience
Summary: With growing interest in utilizing semiochemicals to control pest species, recent investigations have begun to consider semiochemicals to control outbreaks of crown-of-thorns starfish (CoTS; Acanthaster cf.
Richard J. Harris, Adam K. Hillberg, Lee D. Bastin, Blake S. Lausen, Saowaros Suwansa-Ard, Tianfang Wang, Abigail Elizur, Sakura Kikuchi, Keisuke Nakashima, Noriyuki Satoh, Cherie A. Motti, Scott F. Cummins   +11 more
doaj  

Complex host/symbiont integration of a multi-partner symbiotic system in the eusocial aphid Ceratovacuna japonica

iScience, 2022
Summary: Some hemipteran insects rely on multiple endosymbionts for essential nutrients. However, the evolution of multi-partner symbiotic systems is not well-established.
Shunta Yorimoto, Mitsuru Hattori, Maki Kondo, Shuji Shigenobu   +3 more
doaj