Results 51 to 60 of about 360,124 (306)

Evolutionary Biology for the 21st Century

PLoS Biology, 2013
New theoretical and conceptual frameworks are required for evolutionary biology to capitalize on the wealth of data now becoming available from the study of genomes, phenotypes, and organisms - including humans - in their natural environments.
H. Allen Orr, Jonathan B. Losos, Stevan J. Arnold, Susanne S. Renner, Robert E. Ricklefs, Dmitri A. Petrov, Thomas L. Turner, Antónia Monteiro, Hopi E. Hoekstra, David S. Hibbett, Gill Bejerano, Pamela S. Soltis, Craig Moritz, Craig Moritz, David P. Mindell, Edmund D. Brodie   +15 more
openaire   +6 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Deciphering genetic adaptations of Old World camels through comparative genomic analyses across all camelid species

iScience
Summary: Old World camels exhibit many unique traits for adaptations to desert environments, distinct from New World camels within the same family. Here, we conducted a comparative genomic analysis of three Old World camel species relative to four New ...
Xin Guo, Jirimutu, Liang Ming, Zhen Wang   +3 more
doaj   +1 more source

The PWWP domain and the evolution of unique DNA methylation toolkits in Hymenoptera

iScience, 2023
Summary: DNMT3 in Hymenoptera has a unique duplication of the essential PWWP domain. Using GST-tagged PWWP fusion proteins and histone arrays we show that these domains have gained new properties and represent the first case of PWWP domains binding to ...
Robert Kucharski, Nancy Ellis, Tomasz P. Jurkowski, Paul J. Hurd, Ryszard Maleszka   +4 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

A family of crown-of-thorns starfish spine-secreted proteins modify adult conspecific behavior

iScience
Summary: With growing interest in utilizing semiochemicals to control pest species, recent investigations have begun to consider semiochemicals to control outbreaks of crown-of-thorns starfish (CoTS; Acanthaster cf.
Richard J. Harris, Adam K. Hillberg, Lee D. Bastin, Blake S. Lausen, Saowaros Suwansa-Ard, Tianfang Wang, Abigail Elizur, Sakura Kikuchi, Keisuke Nakashima, Noriyuki Satoh, Cherie A. Motti, Scott F. Cummins   +11 more
doaj   +1 more source

Environmental influence on Pristionchus pacificus mouth form through different culture methods

Scientific Reports, 2017
Environmental cues can impact development to elicit distinct phenotypes in the adult. The consequences of phenotypic plasticity can have profound effects on morphology, life cycle, and behavior to increase the fitness of the organism.
Michael S. Werner, Bogdan Sieriebriennikov, Tobias Loschko, Suryesh Namdeo, Masa Lenuzzi, Mohannad Dardiry, Tess Renahan, Devansh Raj Sharma, Ralf J. Sommer   +8 more
doaj   +1 more source

Evolutionary Biology Needs Wild Microbiomes

Frontiers in Microbiology, 2017
The microbiome is a vital component to the evolution of a host and much of what we know about the microbiome derives from studies on humans and captive animals.
Sarah M. Hird
doaj   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

FEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic, Morana Dulic, Ita Gruic‐Sovulj   +2 more
wiley   +1 more source

TLR7 neo-functionalizes to sense dsRNA and trigger antiviral and antibacterial immunity in non-tetrapod vertebrates

iScience, 2023
Summary: TLR7 plays a crucial role in sensing viral ssRNA and initiating immune responses. Piscine TLR7 also responds to dsRNA challenge. dsRNA exists in almost all the viruses at specific stages.
Rui Jiang, Wentao Zhu, Zhiwei Liao, Chunrong Yang, Jianguo Su   +4 more
doaj   +1 more source