Results 51 to 60 of about 935,716 (329)

The Morphogenesis Of Evolutionary Developmental Biology [PDF]

open access: yes, 2003
The early studies of evolutionary developmental biology (Evo-Devo) come from several sources. Tributaries flowing into Evo-Devo came from such disciplines as embryology, developmental genetics, evolutionary biology, ecology, paleontology, systematics ...
Gilbert, Scott F.
core   +2 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Opposing effects of plant traits on diversification

open access: yesiScience, 2023
Summary: Species diversity can vary dramatically across lineages due to differences in speciation and extinction rates. Here, we explore the effects of several plant traits on diversification, finding that most traits have opposing effects on ...
Bruce Anderson   +16 more
doaj  

Evolutionary Biology: Speciation on Islands [PDF]

open access: yesCurrent Biology, 2010
One of the strongest rules of biological diversity - the observation that more species live on large islands than on small ones - is usually attributed to the balance between colonization and extinction. But speciation on islands cannot be ignored.
Richard E. Glor, Daven C. Presgraves
openaire   +3 more sources

Evolution and Culture [PDF]

open access: yes, 2011
The goal of cross-cultural psychology to identify and explain similarities and differences in the behavior of individuals in different cultures requires linking human behavior to its context (Cole, Meshcheryakov & Ponomariov, 2011).
Chasiotis, Athanasios
core   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Evolutionary Biology and Rape [PDF]

open access: yes, 1999
This article queries whether an evolutionary analysis of rape may be more compelling in explaining a rape victim\u27s fear than a defendant\u27s sexual aggression. Such a victim-oriented approach could help legal decisionmakers assess the reasonableness
Denno, Deborah W.
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Chromatin remodelling and antisense-mediated up-regulation of the developmental switch gene eud-1 control predatory feeding plasticity

open access: yesNature Communications, 2016
In the nematode Pristionchus pacificus, a developmental switch, the sulfatase eud-1, controls mouth-form plasticity. Here, the authors show that mutations in two conserved histone modifying enzymes mimic the eud-1 phenotype, in part mediated by an ...
Vahan Serobyan   +7 more
doaj   +1 more source

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