Results 81 to 90 of about 389,475 (313)
Neutrality: A Necessity for Self-Adaptation [PDF]
Proceedings of the Congress on Evolutionary Computation (CEC
2002), 1354-1359., 2002 Self-adaptation is used in all main paradigms of evolutionary computation to increase efficiency. We claim that the basis of self-adaptation is the use of neutrality. In the absence of external control neutrality allows a variation of the search distribution without the risk of fitness loss.
arxiv
What’s wrong with evolutionary biology? [PDF]
Biology & Philosophy, 2016 There have been periodic claims that evolutionary biology needs urgent reform, and this article tries to account for the volume and persistence of this discontent. It is argued that a few inescapable properties of the field make it prone to criticisms of predictable kinds, whether or not the criticisms have any merit. For example, the variety of living
openaire +3 more sources
Evolutionary foundations for cancer biology [PDF]
Evolutionary Applications, 2013 AbstractNew applications of evolutionary biology are transforming our understanding of cancer. The articles in this special issue provide many specific examples, such as microorganisms inducing cancers, the significance of within‐tumor heterogeneity, and the possibility that lower dose chemotherapy may sometimes promote longer survival.
C. Athena Aktipis +2 more
openaire +3 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Protocol for an agent-based model of recombination in bacteria playing a public goods game
STAR Protocols, 2023 Summary: Agent-based models are composed of individual agents coded for traits, such as cooperation and cheating, that interact in a virtual world based on defined rules.
Isaiah Paolo A. Lee +3 more
doaj
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Robust 3D modeling reveals spatiosyntenic properties of animal genomes
iScience, 2023 Summary: Animal genomes are organized into chromosomes that are remarkably conserved in their gene content, forming distinct evolutionary units (synteny).
Tereza Clarence +5 more
doaj
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion
Advanced Engineering Materials, EarlyView., 2023 Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal +5 more
wiley +1 more source
GC3 Biology in Eukaryotes and Prokaryotes [PDF]
DNA Methylation - From Genomics to Technology, 2012, pp 55-68, 2012 We describe the distribution of Guanine and Cytosine (GC) content in the third codon position (GC3) distributions in different species, analyze evolutionary trends and discuss differences between genes and organisms with distinct GC3 levels. We scrutinize previously published theoretical frameworks and construct a unified view of GC3 biology in ...
arxiv