Results 91 to 100 of about 3,379,728 (314)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Jixie chuandong, 2005 The method of rigid-body guidance synthesis of adjustable mechanisms for multiple alternation tasks based on evolutionary computation is proposed.The mechanism optimization model of multi-tasks is established,and the global optimization solution will be ...
杨志刚 +3 more
doaj
RFreak-An R-package for evolutionary computation [PDF]
RFreak is an R package providing a framework for evolutionary computation. By enwrapping the functionality of an evolutionary algorithm kit written in Java, it offers an easy way to do evolutionary computation in R.
Nunkesser, Robin
core
Evolutionary Computation for CSP’s [PDF]
, 2003 Los problemas de Scheduling son un paradigma de la familia de problemas CSP. En este artículo presentamos algunas técnicas de resolución mediante Algoritmos Genéticos.
Alonso González, César Luis +3 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Interactive Evolutionary Computation for Analyzing Human Awareness Mechanisms
Applied Computational Intelligence and Soft Computing, 2012 We discuss the importance of establishing awareness science and show the idea of using interactive evolutionary computation (IEC) as a tool for analyzing awareness mechanism and making awareness models.
Hideyuki Takagi
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Efficient Computation of Fitness Function for Evolutionary Clustering
Mendel, 2019 Evolutionary algorithms (EAs) are random search heuristics which can solve various optimization problems. There are plenty of papers describing different approaches developed to apply evolutionary algorithms to the clustering problem, although none of ...
Sergey Muravyov +3 more
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
IEEE Transactions on Evolutionary Computation Society Information [PDF]
, 2020 Gary Fogel +10 more
openalex +1 more source