Results 81 to 90 of about 240,484 (316)
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Computation Environments, An Interactive Semantics for Turing Machines (which P is not equal to NP considering it) [PDF]
, 2012 To scrutinize notions of computation and time complexity, we introduce and formally define an interactive model for computation that we call it the \emph{computation environment}.
Ramezanian, Rasoul
core
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Jixie chuandong, 2005 The method of rigid-body guidance synthesis of adjustable mechanisms for multiple alternation tasks based on evolutionary computation is proposed.The mechanism optimization model of multi-tasks is established,and the global optimization solution will be ...
杨志刚 +3 more
doaj
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
Interactive Evolutionary Computation for Analyzing Human Awareness Mechanisms
Applied Computational Intelligence and Soft Computing, 2012 We discuss the importance of establishing awareness science and show the idea of using interactive evolutionary computation (IEC) as a tool for analyzing awareness mechanism and making awareness models.
Hideyuki Takagi
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
The Evolution of Evolutionary Computation [PDF]
, 2003 Evolutionary computation has enjoyed a tremendous growth for at least a decade in both its theoretical foundations and industrial applications. Its scope has gone far beyond binary string optimisation using a simple genetic algorithm. Many research topics in evolutionary computation nowadays are not necessarily ”genetic” or ”evolutionary” in any ...
openaire +3 more sources
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Evolutionary Multi-Objective Membrane Algorithm
IEEE Access, 2020 Recent advances in evolutionary algorithms based on membrane computing have shown that the mechanism of membrane computing is an effective way to solve optimization problems. In this work, we propose a new evolutionary multi-objective algorithm that uses
Chuang Liu +3 more
doaj +1 more source