Results 81 to 90 of about 258,840 (301)

Evolutionary Computation for Feature Manipulation in Salient Object Detection [PDF]

, 2020
Shima Afzali Vahed Moghaddam
openalex   +1 more source

Elitism Levels Traverse Mechanism For The Derivation of Upper Bounds on Unimodal Functions [PDF]

, 2012
In this article we present an Elitism Levels Traverse Mechanism that we designed to find bounds on population-based Evolutionary algorithms solving unimodal functions. We prove its efficiency theoretically and test it on OneMax function deriving bounds c{
Ter-Sarkisov, Aram
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

IEEE Transactions on Evolutionary Computation Publication Information [PDF]

, 2023
Carlos Coello Coello, David Fogel, Thomas ck, Wolfgang Banzhaf, Carola Doerr, Liang Feng, Jonathan Fieldsend, Abhishek Gupta, Pauline Haddow, Julia Handl, Mark Harman, Mard Helbig, Malcolm Heywood, Sheridan Houghten, Han Huang, Thomas Jansen, Min Jiang, Albert Lam, Jing Liang, Qiuzhen Lin, Jialin Liu, Markus Olhofer, Pietro Oliveto, Beatrice Ombuki-Berman, Soon Ong, Chao Qian, Kai Qin, Luis Santana-Quintero, Oliver Sch, tze Cinvestav-Ipn, Mexico Hemant, Kumar Singh, K Tang, Chuan-Kang Ting, Y Tian, Heike Trautmann, Handing Wang, Ling Wang, Rui Wang, Yong Wang, Shengxiang Yang, Georgios Yannakakis, Xingyi Zhang, Saifur Rahman, Rabab Ward, Thomas Coughlin, Sergio Benedetto, Forrest Wright, Jill Gostin, Mary Randall, Y Yuan, K Liu, John Verboncoeur, Eduardo Palacio, Stephanie White, Sophia Muirhead, Cherif Amirat, Cecilia Jankowski, Geographic Activities, Russell Harrison, Konstantinos Karachalios, Karen Hawkins, Jamie Moesch, Educational Activities, Steven Heffner, Donna Hourican, Thomas Siegert, Mary Ward-Callan, Dawn Melley, Kevin Lisankie, Peter Tuohy, Jeffrey Cichocki, Neelam Khinvasara   +72 more
openalex   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Evolutionary Computation for CSP’s [PDF]

, 2003
Los problemas de Scheduling son un paradigma de la familia de problemas CSP. En este artículo presentamos algunas técnicas de resolución mediante Algoritmos Genéticos.
Alonso González, César Luis, Puente Peinador, Jorge, Rodríguez Vela, María del Camino, Varela Arias, José Ramiro   +3 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Optimal adaptive coordination of overcurrent relays in power systems protection using a new hybrid metaheuristic algorithm

IET Renewable Power Generation
Advent of distributed generation and progression towards an intelligent grid infrastructure within the domain of contemporary electrical power systems have created dynamic load profiles.
Samira Sadeghi, Ali Hesami Naghshbandy, Parham Moradi, Abed Bagheri   +3 more
doaj   +1 more source