Results 171 to 180 of about 1,190,012 (253)

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li   +15 more
wiley   +1 more source

Evolutionary games, climate and the generation of diversity. [PDF]

open access: yesPLoS One, 2017
Friedman D   +3 more
europepmc   +1 more source

The Simple Geometry of Perfect Information Games [PDF]

open access: yes
Perfect information games have a particularly simple structure of equilibria in the associated normal form. For generic such games each of the finitely many connected components of Nash equilibria is contractible. For every perfect information game there
Demichelis, Stefano   +2 more
core  

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng   +17 more
wiley   +1 more source

Spatial evolutionary games with weak selection. [PDF]

open access: yesProc Natl Acad Sci U S A, 2017
Nanda M, Durrett R.
europepmc   +1 more source

Evolution in Symmetric Incomplete Information Games [PDF]

open access: yes
The paper compares two models of evolution in symmetric two-player games with incomplete information. One model postulates that the type of a player is fixed, and evolution works within types. In the other model type-contingent strategies evolve.
Erwin Amann, Alex Possajennikov
core  

Bacteria‐Derived 1‐Allylpiperazine Alleviates Symptoms of Parkinson's Disease Model by Promoting Autophagy

open access: yesAdvanced Science, EarlyView.
Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu   +12 more
wiley   +1 more source

Spatiotemporal Regulation of Hierarchical Assembly of Hydroxyapatite for Enamel Remineralization

open access: yesAdvanced Science, EarlyView.
Biomimetic repair exhibits unique advantages for enamel regeneration compared with conventional clinical treatments. An enzymatic mineralization system (EMS) is developed, where the resulting HAP nanorods hierarchically assemble into a highly ordered structure on the enamel surface through the spatiotemporal modulation of interfacial energies of ...
Zhenhang Tang   +15 more
wiley   +1 more source

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