Results 51 to 60 of about 318,286 (260)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Aggregative context-aware fitness functions based on feature selection for evolutionary learning of characteristic graph patterns

Vietnam Journal of Computer Science, 2018
We propose aggregative context-aware fitness functions based on feature selection for evolutionary learning of characteristic graph patterns. The proposed fitness functions estimate the fitness of a set of correlated individuals rather than the sum of ...
Fumiya Tokuhara, Tetsuhiro Miyahara, Tetsuji Kuboyama, Yusuke Suzuki, Tomoyuki Uchida   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Rethinking Phenotypic Categorization: Evidence From Morphological and Life‐History Traits in Spiny Lizards (Sceloporus)

Ecology and Evolution
The evolution of phenotype has historically been studied by classifying traits into categories, as traits within each category often exhibit close associations. However, these categories are not independent of one another.
Isaac Emmanuell Diaz‐Ortega, José Jaime Zúñiga‐Vega, Oscar Flores‐Villela, Hibraim Adán Pérez‐Mendoza   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Socio‐eco‐evolutionary dynamics in cities

Evolutionary Applications, 2021
Cities are uniquely complex systems regulated by interactions and feedbacks between nature and human society. Characteristics of human society—including culture, economics, technology and politics—underlie social patterns and activity, creating a ...
Simone Des Roches, Kristien I. Brans, Max R. Lambert, L. Ruth Rivkin, Amy Marie Savage, Christopher J. Schell, Cristian Correa, Luc De Meester, Sarah E. Diamond, Nancy B. Grimm, Nyeema C. Harris, Lynn Govaert, Andrew P. Hendry, Marc T. J. Johnson, Jason Munshi‐South, Eric P. Palkovacs, Marta Szulkin, Mark C. Urban, Brian C. Verrelli, Marina Alberti   +19 more
doaj   +1 more source

Evolutionary pathways to convergence in plumage patterns [PDF]

BMC Evolutionary Biology, 2016
BACKGROUND: Avian plumage is ideal for investigating phenotypic convergence because of repeated evolution of the same within-feather patterns. In birds, there are three major types of regular patterns within feathers: scales, bars and spots. Existing models of within-feather pattern development suggest that scales have the simplest developmental ...
Gluckman, Thanh-Lan, Mundy, Nicholas I
openaire   +4 more sources

Non-linear correlation analysis between internet searches and epidemic trends

Frontiers in Public Health
IntroductionThis study uses a non-linear model to explore the impact mechanism of change rates between internet search behavior and confirmed COVID-19 cases.
Yongzhang He, Lingshi Ran, Yang Wang, Fengxiang Huang, Yixue Xia   +4 more
doaj   +1 more source

Evolutionary patterns of RNA-based duplication in non-mammalian chordates. [PDF]

PLoS ONE, 2011
The role of RNA-based duplication, or retroposition, in the evolution of new gene functions in mammals, plants, and Drosophila has been widely reported. However, little is known about RNA-based duplication in non-mammalian chordates.
Ming Chen, Ming Zou, Beide Fu, Xin Li, Maria D Vibranovski, Xiaoni Gan, Dengqiang Wang, Wen Wang, Manyuan Long, Shunping He   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source