Results 81 to 90 of about 1,877,358 (268)

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert   +8 more
wiley   +1 more source

Evolutionary perspectives in publications across subfields of psychology

open access: yes, 2017
Across time, there has been variability in the degree to which evolutionary perspectives and explanations have been integrated within the prevailing theoretical perspectives in psychology as a whole and within the various subfields of psychology.
Hart, Christian L.   +2 more
core   +2 more sources

Evolutionary psychology and perfume design

open access: yes, 2012
We argue that the process of perfume design would be enhanced if it was developed with greater understanding of the communicative value of the underlying body odour of the individual who uses it? Evolutionary psychology has, and will continue to, produce
Roberts, S Craig
core  

Evolutionary Psychology: new perspectives on sport marketing?

open access: yes, 2010
Evolutionary psychologists view the human mind as a product of evolution. This paper considers how evolutionary psychology can be employed by sport marketing practitioners to better understand sport consumption.
Bob Stewart   +4 more
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

Austrian Economics, Evolutionary Psychology and Methodological Dualism: Subjectivism Reconsidered [PDF]

open access: yes
The methodological individualism and subjectivism of the Austrian tradition in economics is often associated with a methodological dualism, i.e. the claim that the nature of its subject matter, namely purposeful and intentional human action, requires ...
Vanberg, Viktor J.
core  

Highly‐Time‐Resolved Measurements of Tryptophan's Distribution and Homeostatic Regulation in Live, Intact Animals

open access: yesAdvanced Science, EarlyView.
Using a novel, aptamer‐based biosensor, here we have performed 20‐s‐resolved, in situ measurements of plasma‐free tryptophan in the jugular veins of live rats (blue). This unprecedented time‐resolution provides insights into the regulation of tryptophan metabolism in live, intact animals.
Yuyang Wu   +7 more
wiley   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

open access: yesAdvanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore   +6 more
wiley   +1 more source

Evolutionary Cognitive Psychology

open access: yes, 2005
The usual approach to studying cognition in evolutionary psychology is in terms of information-processing mechanisms selected to solve domain-specific problems. But there are also important selective forces operating widely across domains, leading to common design features in many cognitive systems.
Todd, P. M., Hertwig, R., Hoffrage, U.
openaire   +4 more sources

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