Results 91 to 100 of about 1,952,937 (282)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Dynamic spectrum access mechanism based on graphical evolutionary game in radio networks
In order to realize efficient data transmission for users in radio networks,a dynamic spectrum access mechanism based on graphical evolutionary game was proposed for the bounded rationality characteristic of users,while graphical game can better reflect ...
Fang-wei LI, Ying-hui YUAN, Jiang ZHU
doaj +2 more sources
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
Evolution of intrinsic disorder in the structural domains of viral and cellular proteomes
Intrinsically disordered regions are flexible regions that complement the typical structured regions of proteins. Little is known however about their evolution.
Fizza Mughal, Gustavo Caetano-Anollés
doaj +1 more source
Literary journalhttps://nwcommons.nwciowa.edu/spectrum/1014/thumbnail ...
Spectrum Contributors,
core
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
b-Glucans, as biologically active polysaccharides, have been used for decades but only recently have become a focus of evolutionary studies. As b-glucans are shown to be active in all animal species studied - from earthworms to humans - we can safely ...
V Vetvicka, P Sima
doaj
Literary journalhttps://nwcommons.nwciowa.edu/spectrum/1012/thumbnail ...
Spectrum Contributors,
core
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Evolutionary Spectrum and Bispectrum Estimation of a Nonstationary Process
The modeling of a non-stationary process is a problem of great interest and has many applications in diverse fields in signal processing. In this paper, an algorithm for estimating the shift- variant (SV) parameters of a non-stationary process, using orthogonal projection, is proposed.
openaire +1 more source

