Results 111 to 120 of about 868,272 (341)
Outlining the distinguishing characteristics of an evolutionary theory of innovation [PDF]
This paper discusses notions of theory in relation to evolutionary understandings of innovation. It starts by empirically demonstrating the relevance of evolutionary perspectives – broadly defined – for understanding the “basics of what’s going on” in ...
Tommy Clausen
core
Linking pattern to process in cultural evolution: explaining material culture diversity among the Northern Khanty of Northwest Siberia [PDF]
, 2009 Book description: This volume offers an integrative approach to the application of evolutionary theory in studies of cultural transmission and social evolution and reveals the enormous range of ways in which Darwinian ideas can lead to productive ...
Jordan, P.
core
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Theory of the Three-Group Evolutionary Minority Game
, 2004 Based on the adiabatic theory for the evolutionary minority game (EMG) that we proposed earlier[1], we perform a detail analysis of the EMG limited to three groups of agents.
BAOSHENG YUAN +6 more
core +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
On an Evolutionary Foundation of Neuroeconomics [PDF]
Neuroeconomics focuses on brain imaging studies mapping neural responses to choice behavior. Economic theory is concerned with choice behavior but it is silent on neural activities.
Burkhard C. Schipper
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The Scope of Reciprocal Causation
Philosophy, Theory, and Practice in BiologyThe role of reciprocal causation in the Extended Evolutionary Synthesis (EES) is controversial. On the one hand, reciprocal causation is considered a key innovation of EES, thereby justifying EES’s existence.
Yasmin Haddad
doaj +2 more sources
The evolutionary theory of the firm: Routines, complexity and change [PDF]
This paper provides an overview on the evolutionary theory of the firm. The specific feature of the evolutionary approach is that it explains the adaptive behaviors of firms through the tension between innovation and selection.
Werner Hölzl
core
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source