Results 101 to 110 of about 868,272 (341)
Zygon, 2020 The renewal of the concept of continuous creation follows two steps: (1) an establishment of the concept of novelty in an exercise of philosophy of nature, as a means of interpreting the scientific discourse concerning the evolution of life; (2 ...
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FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Session 2: Female Orgasms and Evolutionary Theory [PDF]
, 2002 Proceedings of the Pittsburgh Workshop in History and Philosophy of Biology, Center for Philosophy of Science, University of Pittsburgh, March 23-24 2001 Session 2: Female Orgasms and Evolutionary ...
Arnold, Karen +3 more
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
An Evolutionary Theory for the Variability Hypothesis
, 2020 An elementary biostatistical theory based on a selectivity-variability principle is proposed to address a question raised by Charles Darwin, namely, how one sex of a sexually dimorphic species might tend to evolve with greater variability than the other ...
Hill, Theodore P.
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Perspective: the evolution of hormones and person perception—a quantitative genetic framework
Frontiers in PsychologyEvolutionary biology provides a unifying theory for testing hypotheses about the relationship between hormones and person perception. Person perception usually receives attention from the perspective of sexual selection.
Christopher I. Gurguis +2 more
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Group theory, group actions, evolutionary algorithms, and global optimization [PDF]
, 2012 Andrew Clark
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