Results 91 to 100 of about 868,272 (341)
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Kant’s Moral Theory Meets Evolutionary Theory [PDF]
Journal of Philosophical InvestigationsThis paper delves into the intersection between Kant’s moral theory and evolutionary perspectives on personhood. It explores how Kant’s emphasis on rationality in moral agency aligns with evolutionary studies on the development of moral behaviors.
Alireza Mansouri
doaj +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
RELATIONSHIPS BETWEEN SEXUAL BEHAVIOR AND PERSONALITY IN THE CONTEXT OF SEXUAL DIMORPHISM [PDF]
Psihologija, 2009 The aim of this study was to examine the structure and intensity of relation-ships between dimensions of sexual behavior and personal characteristics in the context of sexual dimorphism. The sample included 233 participants (both genders, mean age 29,34).
Bojana Dinic, Goran Knezevic
doaj
The cell's self-generated “electrome”: The biophysical essence of the immaterial dimension of Life?
Communicative & Integrative Biology, 2016 In the classical “mind-body” wording, “body” is usually associated with the “mass aspect” of living entities and “mind” with the “immaterial” one. Thoughts, consciousness and soul are classified as immaterial.
Arnold De Loof
doaj +1 more source
(Re‐) Defining evolutionary medicine
Ecology and Evolution, 2020 The applicability of evolutionary biology principles to diseases has been largely questioned by the medical field. While Evolutionary Medicine (EM) developed in part to lessen this gap, EM is an independent field from both evolution and medicine, whose ...
Jacqueline Moltzau Anderson +1 more
doaj +1 more source
, 2015 Evolutionary game theory is a powerful framework for studying evolution in populations of interacting individuals. A common assumption in evolutionary game theory is that interactions are symmetric, which means that the players are distinguished by only ...
Hauert, Christoph, McAvoy, Alex
core +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source