Results 71 to 80 of about 6,349,669 (299)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The Curatorial Turn in the Darwin Year 2009
19, 2010 The concept of the ‘curatorial turn’ was originally coined by Daniel Birnbaum, director of the 2009 Venice Biennale, and denoted interest in the exhibition as an alternative to the book by contemporary philosophers such as Jean-François Lyotard and Bruno
Julia Voss
doaj +2 more sources
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Evolutionary Theory in the 1920s: The Nature of the 'Synthesis' [PDF]
, 2002 This paper analyzes the development of evolutionary theory in the period from 1918 to 1932. It argues that: (i) Fisher's work in 1918 constitutes a not fully satisfactory reduction of biometry to Mendelism; (ii) that there was a synthesis in the 1920s ...
Sarkar, Sahotra
core
Evolutionary Theory and the Epistemology of Science [PDF]
, 2013 Evolutionary theory is a paradigmatic example of a well-supported scientific theory. In this chapter we consider a number of objections to evolutionary theory, and show how responding to these objections reveals aspects of the way in which scientific ...
Weslake, Brad, McCain, Kevin
core +3 more sources
The Generalized Price Equation: Forces That Change Population Statistics
Frontiers in Ecology and Evolution, 2020 The Price equation partitions the change in the expected value of a population measure. The first component describes the partial change caused by altered frequencies. The second component describes the partial change caused by altered measurements.
Steven A. Frank, William Godsoe
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Evolutionary Game Theory and Thorstein Veblen’s Evolutionary Economics: Is EGT Veblenian? [PDF]
This essay provides an approach to the analysis of the link between Thorstein Veblen's evolutionary approach and evolutionary game theory (EGT). We shed some light on the potential contribution of Veblen's theory of socioeconomic evolution to the ...
Villena, Mauricio G. +1 more
core
This work presents the evolutionary growth theory, which studies the drivers and patterns of technological change and production together with the (imperfect) mechanisms of coordination among a multitude of firms. This requires to studies economies as complex evolving systems, i.e.
Dosi, Giovanni, Roventini, Andrea
openaire +3 more sources