Results 101 to 110 of about 888,235 (335)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Permeability evolution across carbonate hosted normal fault zones [PDF]

open access: green, 2016
Thomas J. Haines   +3 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Bond competition and phase evolution on the IrTe2 surface [PDF]

open access: bronze, 2014
Qing Li   +8 more
openalex   +1 more source

Social Darwinism [PDF]

open access: yes, 2009
El món del saber mai no fou el mateix a partir del 24 de novembre de 1859. Fins i tot, les persones a qui més plau posar èmfasi en la dimensió anònima i col·lectiva de l'avenç científic es veuen obligades a acceptar la fulminant aportació d'una sola i ...
Giner i de San Julián, Salvador
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Genotype and evolutionism [PDF]

open access: yes, 2011
Geni su nosioci nasljednih osobina koji kodiraju za sintezu bjelančevina. Tijekom evolucije geni se mijenjaju putem prirodne selekcije, mutacija, genetičkog drifta i protoka gena.
Andrić, Vedrana
core   +2 more sources

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