Results 101 to 110 of about 12,015 (284)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Epigênese e epigenética: as muitas vidas do vitalismo ocidental

open access: yesHorizontes Antropológicos
Resumo A análise da história e dos usos contemporâneos dos termos epigênese, atribuído a Aristóteles, e epigenética, criado no século XX pelo biólogo C. H.
Gláucia Silva   +1 more
doaj   +1 more source

Eucharist and Sacrifice [PDF]

open access: yes
An exploration of different understandings of 'sacrifice' by Christian theologians, and how these affect our understanding of the eucharist, especially in the light of the mimetic of Rene ...
Kirwan, Michael
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Genotype and evolutionism [PDF]

open access: yes, 2011
Geni su nosioci nasljednih osobina koji kodiraju za sintezu bjelančevina. Tijekom evolucije geni se mijenjaju putem prirodne selekcije, mutacija, genetičkog drifta i protoka gena.
Andrić, Vedrana
core   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Evolução e desígnio em Hayek

open access: yesDados: Revista de Ciências Sociais, 1999
In an examination of Hayek?s social philosophy, the article seeks to distinguish between socio-epistemological arguments, which postulate the radical ignorance of social actors, and the conservative political conclusions usually associated with Hayek?s ...
Kerstenetzky Celia Lessa
doaj  

Data on the identification of microsatellite markers in Eisenia fetida and Eisenia andrei. [PDF]

open access: yesData Brief, 2022
Jaskulak M   +6 more
europepmc   +1 more source

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