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The phenomenon of globalization, which is well known in the economy, can nowadays be observed also in the area of science. It is based on the fact that more and more scientific disciplines are applying the same explanatory principle, namely the theory of evolution. Therefore, every development, including that of man, according to the pattern of genetic
openaire +2 more sources
A neglected conceptual problem regarding phenotypic plasticity's role in adaptive evolution: The importance of genetic covariance and social drive [PDF]
Nathan W. Bailey +5 more
openalex +1 more source
Foucauldian Peacekeeping: On the Dispersion of Power and the Futility of Change [PDF]
Foucault is widely known for the radical nature of his work, for his idiosyncratic approach to history, and for his reconfiguration of the concept of power. Curiously though, his conceptions of history and power might act to undermine their potential to
Allen, Ansgar
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We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Regional science at the turn of the century: Reflections on its epistemological status [PDF]
As a contribution to the current debate on the state-of-the art of regional science, this paper presents some reflections on the epistemological and methodological status of the discipline as we approach the turn of the century.
Angela Spence, Giovanni A. Rabino
core
Ciencia y creencia en la construcción del concepto de religión paleolítica [PDF]
The study of prehistory established itself as a scientific discipline during the second half of the nineteenth century. The main issues discussed by this new science centered on the origins of humankind, society, technology, art and religion; this ...
Palacio-Pérez, Eduardo
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A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The book develops a scientific approach to the phenomenon of religion. It is the conviction of the author that such an approach can only be comparative in nature, in order to overcome centuries of religiously biased views on religion.
Pinxten, Hendrik
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Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source

