Results 81 to 90 of about 12,015 (284)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Un manuscrit de Michel Foucault sur la psychanalyse
Astérion, 2019 In this manuscript of the early 1950s, Foucault outlines the path of Freud’s psychoanalysis from a biological approach based on the evolutionary perspective to disease, towards the understanding of its psychological significance.
Michel Foucault, Elisabetta Basso
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Darwin Rocks Hegel: Does Nature Have A History? [PDF]
, 2008 In the popular press and the halls of politics, controversies over evolution are increasingly strident these days. Hegel is relevant in this connection, even though he rejected the theories of evolution he knew about, because he wanted rational ...
Kolb, David
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Ce que « sociologiser le biologique » peut bien vouloir dire
TracésBernard Lahire’s last book aims at “sociologising biology” by examining the ethological factors explaining and conditioning human sociality and society. As such, it instead looks like a classical reductionist program to biologise social behaviour (albeit
Chloé Mondémé
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Cahiers Jean Moulin, 2017 In Italy, as in other European countries at the end of the 19th century, the biological theory of evolution and the social darwinism played an important role in the scientific controversies.
Dario Di Cecca
doaj +1 more source
Where did anthropology go?: or the need for 'human nature' [PDF]
, 2004 I was recently asked the question: “Where did anthropology go? ” by a psycholinguist from a famous American university. She was commenting on the fact that she had tried to establish contact with the anthropology department of her institution, hoping ...
Bloch, Maurice
core +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source