Ewing's sarcoma with distant metastasis: A brief note on management and emerging therapies
Ewing’s sarcoma is an aggressive fatal malignancy of bones and soft-tissue. It predominantly affects the young population, with a worldwide incidence of three cases per million. The pelvis, extremities, and ribs are the most common sites.
Girish Gulab Meshram +2 more
doaj +1 more source
Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model. [PDF]
BACKGROUND:Pleomorphic liposarcoma (PLPS) is a rare, heterogeneous and an aggressive variant of liposarcoma. Therefore, individualized therapy is urgently needed.
Dry, Sarah M +16 more
core +3 more sources
Molecular features in a biphenotypic small cell sarcoma with neuroectodermal and muscle differentiation [PDF]
We report a case of a 13-year-old girl with soft tissue sarcoma of the hand, which showed muscle and neuroectodermal immunophenotypes. Molecular studies were performed on RNA collected from fine-needle aspiration (FNA) cytology and ...
Alava, E. (Enrique) de +8 more
core +1 more source
Paratesticular Ewing's sarcoma
This case report follows a 23-year-old man who presented with a painful right scrotal mass which was found to be a paratesticular vascular solid mass on ultrasound, and after uncomplicated orchiectomy, was revealed to be a high-grade extraskeletal Ewing's sarcoma.
Victoria Koshevarova +5 more
openaire +3 more sources
Subungual Ewing sarcoma/PNET tumor family of the great toe: a case report
Ewing's sarcoma is seen mainly in patients less than 18. This aggressive tumor generally affects the axial skeleton and only rarely involves the acral regions. Ewing’s sarcoma in the foot is inordinately scarce.
Fariba Binesh +3 more
doaj +1 more source
Sinonasal Ewing's sarcoma: Recognition and management of a rare disease
Nasal mass in the pediatric population is most commonly benign and thus treated with low suspicion for malignancy. Ewing's sarcoma is the most common pediatric malignancy and usually arises in the diaphysis of long bones.
Zachary D. Urdang +2 more
doaj +1 more source
Ewing’s sarcoma of the right kidney with multiple metastasis on PET/CT
Background Ewing’s sarcoma is categorized as small round cell aggressive tumor which commonly occurs in bone and soft tissue. Primary renal Ewing’s sarcoma is an extremely rare entity and accounts for less than 1% of renal masses.
Man Mohan Singh +4 more
doaj +1 more source
The role of imaging in the evaluation of extraskeletal Ewing’s sarcoma
Primary bone tumours account for 5% of all adolescent and child cancers. When Ewing’s sarcoma arises in soft tissue rather than bone, it is referred to as extraskeletal Ewing’s sarcoma (ESS).
Pieter Barnardt, Francois Roux
doaj +1 more source
Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model. [PDF]
Adult pleomorphic rhabdomyosarcoma (RMS) is a rare and malignant mesenchymal tumor. Recently, we developed a patient-derived orthotopic xenograft (PDOX) model of adult pleomorphic RMS.
Dry, Sarah M +16 more
core
The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing's sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapy. [PDF]
The aim of the present study was to determine the usefulness of a patient-derived orthotopic xenograft (PDOX) nude-mouse model of a doxorubicin-resistant metastatic Ewing's sarcoma, with a unique combination of a FUS-ERG fusion and CDKN2A deletion, to ...
Bouvet, Michael +20 more
core +1 more source

