Results 21 to 30 of about 6,935 (141)

The role of imaging in the evaluation of extraskeletal Ewing’s sarcoma

South African Journal of Radiology, 2013
Primary bone tumours account for 5% of all adolescent and child cancers. When Ewing’s sarcoma arises in soft tissue rather than bone, it is referred to as extraskeletal Ewing’s sarcoma (ESS).
Pieter Barnardt, Francois Roux
doaj   +1 more source

Discovery and Validation of a Compound to Target Ewing’s Sarcoma

Pharmaceutics, 2021
Ewing’s sarcoma, characterized by pathognomonic t (11; 22) (q24; q12) and related chromosomal ETS family translocations, is a rare aggressive cancer of bone and soft tissue.
Ellie Esfandiari Nazzaro, Fahad Y. Sabei, Walter K. Vogel, Mohamad Nazari, Katelyn S. Nicholson, Philip R. Gafken, Olena Taratula, Oleh Taratula, Monika A. Davare, Mark Leid   +9 more
doaj   +1 more source

Identification of Common Oncogenic Genes and Pathways Both in Osteosarcoma and Ewing’s Sarcoma Using Bioinformatics Analysis

Journal of Immunology Research, 2022
This study was aimed at exploring common oncogenic genes and pathways both in osteosarcoma and Ewing’s sarcoma. Microarray data were obtained from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were identified using the
Jingwei Zhang, Junchao Huang, Wenjun Liu, Liang Ding, Dongdong Cheng, Haijun Xiao   +5 more
doaj   +1 more source

Silent Malignant Occipital Swelling

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2018
Ewing's sarcoma commonly reported in long bones and pelvis. Primary Ewing's sarcoma of the cranium is rare. They behave differently from their counterpart involving the long bones. They usually respond well to chemotherapy and radiotherapy.
Sumeet V Sasane, Sushanta K Sahoo, Chhitij Srivastava, Ajay Singh, Bal Krishna Ojha   +4 more
doaj   +1 more source

Primary Ewing’s Sarcoma of the Spine: About a Case

Global Pediatric Health, 2022
Ewing’s sarcoma is a primary malignant bone tumor affecting individuals in the second decade of life. Primary sarcomas of the spine are rare and the occurrence of primary Ewing’s sarcoma in the spine is very rare.
Amine Cherraqi MD, Abir Lemrabet MD, Ibrahima Diallo Dokal MD, Najlae Lrhorfi MD, Hicham Belghiti MD, Nazik Allali PhD, Latifa Chat PhD   +6 more
doaj   +1 more source

Super‐Enhancer‐Driven SOX4/SMAD3 Mediate Membrane Remodeling by Regulating Phospholipid Metabolism to Accelerate Leukemia Progression

Advanced Science, EarlyView.
Chronic myeloid leukemia blast phase (CML‐BP) poses a severe therapeutic challenge. This study reveals that the super‐enhancer‐driven transcription factors SOX4 and SMAD3 form a cooperative axis critical for disease progression. They co‐activate the oncogenic kinase AXL and promote phospholipid remodeling via LPCAT1 to facilitate its signaling ...
Enzhe Lou, Peilong Lai, Guanjie Peng, Bo Lu, Lizhen Jiang, Xinyue Li, Jinghong Chen, Ladi Mo, Qiong Mao, Haichuan Zhang, Jinxin Fang, Yi Meng, Aochu Liu, Yingyin Gao, Andong Huang, Wenhui Lin, Shiwen Hu, Zerong Guan, Xiaolan Ye, Zhenguo Liu, Liling Jiang, Yueyuan Zheng, Xianping Shi   +22 more
wiley   +1 more source

Peripheral primitive neuroendocrine tumor of the chest wall—A case report with pathological correlation

Radiology Case Reports, 2018
Primitive neuroectodermal tumor is a high-grade malignant tumor originating from the neural crest and neuroectoderm, which can be subdivided into central and peripheral categories.
Jidi Gao, MD, Erika Chow, BA, Aishatu Aloma, MD, Payal Gupta, MD   +3 more
doaj   +1 more source

Characterization of inflammatory pseudotumors in a large animal model of liver cancer

Animal Models and Experimental Medicine, EarlyView.
CT images in arterial and portal venous phases of liver lesions in Oncopig. Abstract Background The development of relevant and robust large animal models of hepatocellular carcinoma is needed to test new therapeutic strategies for this disease. Transgenic approaches hold promise in addressing this complex problem. One such model, the Oncopig, has been
Erik N. K. Cressman, Samantha Hicks, Natalie W. Fowlkes, Danielle L. Stolley, Maria Sophia Stenkamp   +4 more
wiley   +1 more source

Ewing’s Sarcoma of the Breast in a Young Woman: A Case Report and Review of the Literature

Frontiers in Oncology, 2022
Ewing’s Sarcoma Family Tumors (ESFT) include classic Ewing’s sarcoma of bone, extra-skeletal Ewing’s sarcoma (EES), malignant small cell tumor of the chest wall (Askin tumor), and soft tissue-based Peripheral Primitive Neuroectodermal tumors (pPNET). The
Simona Papi, Francesca Combi, Francesca Combi, Silvia Segattini, Silvia Accogli, Enza Palma, Anna Gambini, Alessia Andreotti, Gabriele Luppi, Giovanni Tazzioli   +9 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source