Results 21 to 30 of about 7,060 (163)

Discovery and Validation of a Compound to Target Ewing’s Sarcoma

Pharmaceutics, 2021
Ewing’s sarcoma, characterized by pathognomonic t (11; 22) (q24; q12) and related chromosomal ETS family translocations, is a rare aggressive cancer of bone and soft tissue.
Ellie Esfandiari Nazzaro, Fahad Y. Sabei, Walter K. Vogel, Mohamad Nazari, Katelyn S. Nicholson, Philip R. Gafken, Olena Taratula, Oleh Taratula, Monika A. Davare, Mark Leid   +9 more
doaj   +1 more source

The role of imaging in the evaluation of extraskeletal Ewing’s sarcoma

South African Journal of Radiology, 2013
Primary bone tumours account for 5% of all adolescent and child cancers. When Ewing’s sarcoma arises in soft tissue rather than bone, it is referred to as extraskeletal Ewing’s sarcoma (ESS).
Pieter Barnardt, Francois Roux
doaj   +1 more source

Peripheral primitive neuroendocrine tumor of the chest wall—A case report with pathological correlation

Radiology Case Reports, 2018
Primitive neuroectodermal tumor is a high-grade malignant tumor originating from the neural crest and neuroectoderm, which can be subdivided into central and peripheral categories.
Jidi Gao, MD, Erika Chow, BA, Aishatu Aloma, MD, Payal Gupta, MD   +3 more
doaj   +1 more source

Identification of Common Oncogenic Genes and Pathways Both in Osteosarcoma and Ewing’s Sarcoma Using Bioinformatics Analysis

Journal of Immunology Research, 2022
This study was aimed at exploring common oncogenic genes and pathways both in osteosarcoma and Ewing’s sarcoma. Microarray data were obtained from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were identified using the
Jingwei Zhang, Junchao Huang, Wenjun Liu, Liang Ding, Dongdong Cheng, Haijun Xiao   +5 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Silent Malignant Occipital Swelling

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2018
Ewing's sarcoma commonly reported in long bones and pelvis. Primary Ewing's sarcoma of the cranium is rare. They behave differently from their counterpart involving the long bones. They usually respond well to chemotherapy and radiotherapy.
Sumeet V Sasane, Sushanta K Sahoo, Chhitij Srivastava, Ajay Singh, Bal Krishna Ojha   +4 more
doaj   +1 more source

Primary Ewing’s Sarcoma of the Spine: About a Case

Global Pediatric Health, 2022
Ewing’s sarcoma is a primary malignant bone tumor affecting individuals in the second decade of life. Primary sarcomas of the spine are rare and the occurrence of primary Ewing’s sarcoma in the spine is very rare.
Amine Cherraqi MD, Abir Lemrabet MD, Ibrahima Diallo Dokal MD, Najlae Lrhorfi MD, Hicham Belghiti MD, Nazik Allali PhD, Latifa Chat PhD   +6 more
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Ewing’s Sarcoma of the Breast in a Young Woman: A Case Report and Review of the Literature

Frontiers in Oncology, 2022
Ewing’s Sarcoma Family Tumors (ESFT) include classic Ewing’s sarcoma of bone, extra-skeletal Ewing’s sarcoma (EES), malignant small cell tumor of the chest wall (Askin tumor), and soft tissue-based Peripheral Primitive Neuroectodermal tumors (pPNET). The
Simona Papi, Francesca Combi, Francesca Combi, Silvia Segattini, Silvia Accogli, Enza Palma, Anna Gambini, Alessia Andreotti, Gabriele Luppi, Giovanni Tazzioli   +9 more
doaj   +1 more source