Results 61 to 70 of about 6,935 (141)

Efficacy and Safety of Donor Lymphocyte Infusion After Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients

European Journal of Haematology, Volume 116, Issue 4, Page 443-449, April 2026.
ABSTRACT This retrospective study evaluates the efficacy and safety of donor lymphocyte infusion (DLI) after allogeneic hematopoietic stem cell transplantation (HSCT) in children. We describe the long‐term use of preemptive, prophylactic, and therapeutic DLI with a gradual dose increase in half‐log increments.
Dinah Walther, Jana Ernst, Carola Wollenhaupt, Susan Wittig, Manuela Härtel, Grit Brodt, Till Milde, Bernd Gruhn   +7 more
wiley   +1 more source

A rare localization of Ewing's Sarcoma in the coracoid process: A case report and literature review on scapular Ewing's sarcomas

Radiology Case Reports
Ewing's sarcoma can affect any bone. Primary localization in the coracoid process is extremely rare and atypical. In the literature there have been a few reports of Ewing's sarcoma of the scapula.
N. Bahlouli, F. Chait, C. Faraj, S. Choumad, I. Lahlou, N. Allali, M. Maachi, N. Lamalmi, L. Chat, S. El Haddad   +9 more
doaj   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Impact of tissue staining and scanner variation on the performance of pathology foundation models: a study of sarcomas and their mimics

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Histopathological analysis is considered the gold standard for the diagnosis and prognostication of cancer. Recent advances in AI, driven by large‐scale digitisation and pan‐cancer foundation models, are opening new opportunities for clinical integration.
Binghao Chai, Jianan Chen, Paul Cool, Fatine Oumlil, Anna Tollitt, David F Steiner, Tapabrata Chakraborti, Adrienne M Flanagan, Adrienne M Flanagan, Anna Tollit, Fatine Oumlil, Fernanda Amary, Roberto Tirabosco, Nischalan Pillay, Paul Cool, Adam Levine, Sebastian Brandner, Angela Richard‐Londt, Petra Balogh, Phillipe Taniere, Preethi Gopinath, Neil Sebire, Luis Campos, Thomas Jacques, Sarah Coupland, Katalin Boros, Edmund Cheesman, Elizabeth Halloran, Caroline Glennie, Leona Doyle, Adrian Marino‐Enriquez, Jonathan Davey, Hannah Monaghan, Michael Toss, David Hughes, Malee Fernando, David Leff, Patrick Shenjere, Oisin Houghton, Tom McCulloch, Filomena Medeiros, Ann Sandison, Kalnisha Naidoo, Getnet Demissie, Heena Patel, Uchechi Igbokwe, Graham Thwaites, Keeley Thwaites, Ann Fleming, Mercy Berin, Shyamala Fernandez, Rajesh Nalluri, Zahra Atiyyah, Konrad Wolfe, Victoria Hills, Tomos Saunders, Matilda Ralph, Nicholas Southgate, Francesca Maggiani, Zsolt Orosz, Jennifer Brown, Nick Athanasou, Ian Cook, Sarah Oliver, Peter Davis, Shelley Brown, Jasenka Mazibrada, Nathan Asher, Efren Quilala, Dalian Beaver, Izhar Bagwan, Dawn Whyndham, Khin Thway, Michael Hubank, Janet Shipley   +74 more
wiley   +1 more source

Retrotracheal Extraskeletal Ewing’s Sarcoma: Case Report and Discussion on Airway Management

Turkish Archives of Otorhinolaryngology, 2017
Extraskeletal Ewing’s sarcoma is a rare tumor, and the management of airway compromise in case of cervical Ewing’s sarcoma has not been established. This report describes the case of a patient with retrotracheal Ewing’s sarcoma and discusses a successful
Graeme Van Der Meer, Hannah Linkhorn, Maayan Gruber, Murali Mahadevan, Colin Barber   +4 more
doaj   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Integrative Genomic Profiling of Pediatric Solid Tumors Reveals Clinically Relevant Variants and Chromosomal Arm Aneuploidies Signatures

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Pediatric malignancies have emerged as the leading cause of disease‐related mortality in children, exhibiting distinct etiological and molecular characteristics compared to adult cancers. Despite advances in genomic profiling, the molecular landscape of pediatric solid tumors, particularly in Chinese populations, remains ...
Bingxiao Yan, Jinhu Wang, Jieni Xiong, Shuangai Liu, Yinbing Tang, Ziqi He, Hujin Yan, Bize Guo, Chen Chen, Yijie Zhang, Qinfang Zhu, Jiabin Cai, Min He, Xuan Wu, Junqing Mao, Lifeng Zhang, Weizhong Gu, Zhu Zhu, Zheming Li, Rui Xiao, Qiang Shu, Gang Yu, Ting Tao   +22 more
wiley   +1 more source

Adult Primary Spinal Epidural Extraosseous Ewing’s Sarcoma: A Case Report and Review of the Literature

Case Reports in Neurological Medicine, 2016
Background. Extraosseous Ewing’s sarcoma in the spinal epidural space is a rare malignancy, especially in adults. Case Presentation. A 40-year-old male presented with back pain and urinary hesitancy.
Mark Bustoros, Cheddhi Thomas, Joshua Frenster, Aram S. Modrek, N. Sumru Bayin, Matija Snuderl, Gerald Rosen, Peter B. Schiff, Dimitris G. Placantonakis   +8 more
doaj   +1 more source