Results 191 to 200 of about 801,996 (307)

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Development of Microsatellite Markers for Ex Situ Management of the Harpy Eagle Using Next Generation Sequencing. [PDF]

Zoo Biol
Kaizer M, Bittencourt PS, Polo ÉM, Sanaiotti TM, Farias IP, von Fersen L, Hrbek T, Banhos A.   +7 more
europepmc   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Cytokines Adsorption During Ex Situ Machine Perfusion of Liver Grafts from Elderly Donors: A Pilot, Prospective, Randomized Study. [PDF]

Life (Basel)
Cirillo G, Bernardi L, Pezzati D, Franzini M, Balzano E, Tincani G, Bronzoni J, Martinelli C, Trizzino A, Petagna L, Carrai P, Petruccelli S, Vukotic R, Uruci E, Masini M, Babboni S, Del Turco S, Morganti R, De Tata V, Paolicchi A, Biancofiore G, Peris A, Lazzeri C, Basta G, Ghinolfi D.   +24 more
europepmc   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

First report of SARS-CoV-2 co-infection with chronic dermatophytosis in a lion (Panthera leo) ex situ at Colombia. [PDF]

BMC Vet Res
Riva HG, Arrieta-Rangel L, F MD, Gómez-Montoya J, Henao LM, Bello-Lemus Y, Sbriller N, Guerra-Simanca M, Mendoza A, Luna-Rodríguez I, R JG, Arquez M, Anaya-Romero M, Gonzales-Torres H, Acosta-Hoyos AJ.   +14 more
europepmc   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

A distance-based framework for assessing the ex-situ conservation status of plants. [PDF]

PLoS One
Graoui ME, Ghanem ME, Amri M, Hijmans RJ.   +3 more
europepmc   +1 more source

MOx/Rh Metallene with Energetic Interfaces as Efficient Bifunctional Electrocatalyst for Durable Water Splitting

Advanced Science, EarlyView.
 . ABSTRACT Developing excellent activity and stability bifunctional electrocatalysts for alkaline water splitting remains challenging. This work constructs ultrathin MOx/Rh metallene heterostructures (M = Fe, Co, Ni) via atmosphere‐controlled solvothermal synthesis, achieving uniform MOx nanoclusters on Rh metallene with optimized interfaces. The FeOx/
Ruilong Wei, Yuner Lin, Shanshan Ye, Shuo Wang, Jing Gao, Chaochao Tao, Shengqian Wang, Pei Xiong, Hang Zhang, Hualan Xu, Shengliang Zhong   +10 more
wiley   +1 more source

Exploring the Chemical Fingerprint and In Vitro Biocompatibility of Wild-Growing and Ex Situ Cultivated Stachys cretica subsp. cretica in the Same Region (Crete, Greece). [PDF]

Chem Biodivers
Tomou EM, Anagnostou M, Battisti FC, Karioti A, Krigas N, Lagopati N, Skaltsa H.   +6 more
europepmc   +1 more source