Results 221 to 230 of about 801,996 (307)
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Segregate, Test, Observe and Persevere (STOP): strengthening ex situ breeding programs for biodiversity in zoos amid highly pathogenic avian influenza threats - a case approach. [PDF]
Günther A +8 more
europepmc +1 more source
The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu +8 more
wiley +1 more source
Optimal Perfusion Pressure Enhances Donor Heart Preservation During Normothermic Ex Situ Perfusion in a Rat Transplantation Model. [PDF]
Kim DW +6 more
europepmc +1 more source
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang +10 more
wiley +1 more source
Genetic diversity analysis and conservation strategy recommendations for ex situ conservation of Cupressus chengiana. [PDF]
Chen C +5 more
europepmc +1 more source
A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang +15 more
wiley +1 more source
Integrated in situ and ex situ conservation guidelines
Integrated approach to in situ and ex situ conservation including results of the workshop legal instruments protocols for practical approaches for backup in ex situ facilities estimation of implementation costs and application in two ...
openaire +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source

