Results 71 to 80 of about 4,133 (244)

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

Advanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning, Ziqiang Zhou, Bangming Li, Hong Lu, Haoyang Wen, Zhoulong Huang, Gang Li, Ping Hu   +7 more
wiley   +1 more source

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

Photosynthetic parameters of Ulmus minor plantlets affected by irradiance during acclimatization

Biologia Plantarum, 2013
In order to set up large-scale acclimatization protocols of micropropagated plants, an in-depth knowledge of their physiological responses during in vitro to ex vitro transfer is required. This work describes the photosynthetic performance of Ulmus minor
M. C. Dias, G. Pinto, C. M. Correia, J. Moutinho-Pereira, S. Silva, C. Santos   +5 more
doaj   +1 more source

Role of Rahnella aquatilis AZO16M2 in Phosphate Solubilization and Ex Vitro Acclimatization of Musa acuminata var. Valery. [PDF]

Microorganisms, 2023
Landa-Acuña D, Toro M, Santos-Mendoza R, Zúñiga-Dávila D.   +3 more
europepmc   +1 more source

ACCLIMATIZATION OF FATINIA AND KALINA PLANTS MICROCLONALLY PROPAGATED IN VITRO TO EX VITRO CONDITIONS

This study investigated the vegetative development and open-field acclimatization of Fatinia (Physocarpus opulifolius) and Kalina (Viburnum spp.) plants after in vitro propagation and subsequent transplantation into various substrates under greenhouse conditions.
Khojayev, Shomil, Boyjigitov, Fozil, Allayarov, Abdurakhmon, Nurjobov, Abbos, Yusupova, Durdona   +4 more
openaire   +1 more source

Self‐Sustaining Lactate Depletion Nanoplatform Remodels Tumor Microenvironment and Augments Synergistic Photodynamic/Photothermal/Chemodynamic/Starvation Therapy for Eradication of Colon Cancer

Advanced Science, EarlyView.
The HILA nanoplatform integrates HMnO2, LOX, and ICG to orchestrate multimodal therapy (starvation, chemodynamic, photodynamic, and photothermal) for achieving efficient colon cancer eradication. The established HMnO2‐LOX catalytic cycle continuously consumes lactate, acidifys microenvironment, relieves hypoxia, and generats reactive oxygen species ...
Yu‐E. Wang, Shibo Zhao, Wenying Wu, Zhiwei Duan, Yuan Li, Xiangyu Zeng, Liang Hong, Yan Chen, Ling Tao, Kewu Zeng, Chaoda Xiao, Xiangchun Shen   +11 more
wiley   +1 more source

Anatomical characteristics of leaves from Teak (Tectona grandis L.f.)

Evidência, 2009
The in vitro culture promotes changes anatomical, physiological and morphological in plants. The objective of this work was to compare the structural characteristics of leaves of Tectona grandis in in vitro culture and ex vitro.
Paulo Cesar Poeta Fermino, Jonny Everson Scherwinski-Pereira   +1 more
doaj  

Optimizing ex vitro Acclimatization of Cinchona spp.: Towards the establishment of an industrial crop in Colombia

Revista Colombiana de Biotecnología
Efforts to optimize ex vitro transfer techniques of un-rooted in vitro shoots of Cinchona spp. (Rubiaceae) a native tree of the andean forests, are crucial for promoting sustainable cultivation practices of this medicinal plant.
Juan David Saavedra Correa, Silvia Lizette Bustamante Rodriguez, Robert Theiler   +2 more
doaj   +1 more source

In vitro propagation of rare species Rhodiola rosea from Altai Mountains

Turczaninowia, 2018
The techniques of biotechnology are considered promising and highly-demanded for propagation and conservation of rare species of medicinal plants. The variety of natural forms of Rhodiola rosea makes it difficult to develop a single efficient in vitro ...
A.A. Erst, A.S. Erst, A.I. Shmakov
doaj   +1 more source