Results 81 to 90 of about 4,878 (253)

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

Advanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim, In Ah Kwon, Bo Seop Jeong, Hyo Seon Kim, Joo‐Hwan Park, Sung Jean Park, Sang‐Rae Lee, Youngki Lee, Dongwoo Khang   +8 more
wiley   +1 more source

Strategies for Successful Acclimatization and Hardening of In Vitro Regenerated Plants: Challenges and Innovations in Micropropagation Techniques

, 2023
The micropropagation technique serves as an effective approach for conserving and propagating numerous plant species. Challenges to its success encompass explant selection, media composition, hormone concentration, microbial contamination, incubation ...
Joshi, Shivani, Jerin James, Nishesh Sharma, James, Jerin, Nishant Kumar, Sonika Kalia, Shiwani Joshi   +6 more
core   +1 more source

Targeting DNGR‐1 with Fangchinoline Elevates Dendritic Cell Antigen Cross‐Presentation‐Mediated Antitumor Immunity in Melanoma

Advanced Science, EarlyView.
Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao, Zhenyang Ren, Jing Zhou, He Luo, Yuling Li, Dan Chen, Yuxiao Jiang, Canzhe Li, Mengyi Zheng, Anqi Li, Yao Wang, Yang Zhang, Dingye Wang, Yanjun Jiang, Jiangyong Gu, Biaoyan Du, Yafei Shi, Fang Liu, Jianyong Xiao, Kun Wang   +19 more
wiley   +1 more source

In vitro rooting and ex vitro acclimatization protocol for Cordyline terminalis (L.) Kunth

Plant Science Today
An efficient in vitro rooting and ex vitro acclimatization protocol was developed for Cordyline terminalis (L.) Kunth, commonly known as the Ti plant, an economically important ornamental foliage species. The study was conducted at the Biotechnology-cum-Tissue Culture Centre, All India Coordinated Research Project (AICRP) on Floriculture and ...
S J Sweta, T Lilymoony, R K T Hafeef, P Vishal, P Jeegarkumar, S R Madhurjit, U Lalit, S Yandava, J Pratyush, M Kumaresan   +9 more
openaire   +1 more source

Height and number of shoots on the survival and development of micropropagated bamboo plantlets during pre-acclimatization

, 2019
During the in vitro multiplication of bamboo plantlets, it is common the formation of shoots aggregates. Once individualized, these can yield a greater number of plantlets than if planted in clusters.
Frederico Henrique da Silva Costa (6571946), João Bosco de Oliveira Júnior (6571940), Jonny Everson Scherwinski-Pereira (4718340), Paulo Arthur Almeida do Vale (6571937)   +3 more
core   +1 more source

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Photosynthetic parameters of Ulmus minor plantlets affected by irradiance during acclimatization

Biologia Plantarum, 2013
In order to set up large-scale acclimatization protocols of micropropagated plants, an in-depth knowledge of their physiological responses during in vitro to ex vitro transfer is required. This work describes the photosynthetic performance of Ulmus minor
M. C. Dias, G. Pinto, C. M. Correia, J. Moutinho-Pereira, S. Silva, C. Santos   +5 more
doaj   +1 more source

Improved growth and acclimatization of somatic embryo-derived Oplopanax elatus plantlets by ventilated photoautotrophic culture

, 2011
To improve large-scale in vitro production of Oplopanax elatus Nakai, we cultured somatic embryo-derived plantlets under a heterotrophic condition (semi-solid culture with sucrose), photoautotrophic condition (semi-solid culture without sucrose), or ...
S. Y. Park, Y. W. Kim, H. K. Moon, H. N. Murthy   +3 more
core   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

In vitro propagation of rare species Rhodiola rosea from Altai Mountains

Turczaninowia, 2018
The techniques of biotechnology are considered promising and highly-demanded for propagation and conservation of rare species of medicinal plants. The variety of natural forms of Rhodiola rosea makes it difficult to develop a single efficient in vitro ...
A.A. Erst, A.S. Erst, A.I. Shmakov
doaj   +1 more source