Results 51 to 60 of about 892,017 (284)
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Maximum Exact Satisfiability: NP-completeness Proofs and Exact Algorithms
Inspired by the Maximum Satisfiability and Exact Satisfiability problems we present two Maximum Exact Satisfiability problems. The first problem called Maximum Exact Satisfiability is: given a formula in conjunctive normal form and an integer k, is there an assignment to all variables in the formula such that at least k clauses have exactly one true ...
Madsen, B.A., Rossmanith, P.
openaire +3 more sources
Exact algorithms for maximum independent set [PDF]
We show that the maximum independent set problem (MIS) on an $n$-vertex graph can be solved in $1.1996^nn^{O(1)}$ time and polynomial space, which even is faster than Robson's $1.2109^{n}n^{O(1)}$-time exponential-space algorithm published in 1986. We also obtain improved algorithms for MIS in graphs with maximum degree 6 and 7, which run in time of $1.
Xiao, Mingyu, Nagamochi, Hiroshi
openaire +2 more sources
Exact Inference with Approximate Computation for Differentially Private Data via Perturbations
This paper discusses how two classes of approximate computation algorithms can be adapted, in a modular fashion, to achieve exact statistical inference from differentially private data products.
Ruobin Gong
doaj
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Exact and Approximation Algorithms for Clustering [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Agarwal, P. K., Procopiuc, C. M.
openaire +1 more source
Algorithms for the quantitative Lock/Key model of cytoplasmic incompatibility
Cytoplasmic incompatibility (CI) relates to the manipulation by the parasite Wolbachia of its host reproduction. Despite its widespread occurrence, the molecular basis of CI remains unclear and theoretical models have been proposed to understand the ...
Tiziana Calamoneri +4 more
doaj +1 more source
Exact and greedy algorithms of allocating experts to maximum set of programmer teams
The allocation of experts to programmer teams, which meet constraints on professional competences related to programming technologies, languages and tools an IT project specifies is a hard combinatorial problem.
A. A. Prihozhy
doaj +1 more source
A comparison of general-purpose optimization algorithms forfinding optimal approximate experimental designs [PDF]
Several common general purpose optimization algorithms are compared for findingA- and D-optimal designs for different types of statistical models of varying complexity,including high dimensional models with five and more factors.
Garcia-Garcia, Jose Carlos +4 more
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