Results 91 to 100 of about 18,090,173 (384)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Exact controllability for nonlocal semilinear differential inclusions

open access: yesBruno Pini Mathematical Analysis Seminar
In this paper, we investigate the controllability of a class of semilinear differential inclusions in Hilbert spaces. Assuming the exact controllability of the associated linear problem, we establish sufficient conditions for achieving the exact ...
Irene Benedetti, Angelica Palazzoni
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Schrödinger equations in noncylindrical domains: exact controllability

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2006
We consider an open bounded set Ω⊂ℝn and a family {K(t)}t≥0 of orthogonal matrices of ℝn. Set Ωt={x∈ℝn;x=K(t)y,for all y∈Ω}, whose boundary is Γt.
G. O. Antunes   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Partial Exact Controllability of a Nonlinear System

open access: yesRevista Matemática Complutense, 1995
Let \(\Omega\) be a bounded open set in \(\mathbb{R}^n\) with sufficiently smooth boundary \(\Gamma\) and \(Q = (0,T) \times \Omega\), \(\Sigma = (0,T) \times \Gamma\). Consider the coupled equations: \[ u_{tt} - \Delta u + f(\theta) = 0 \quad \theta_t - \Delta \theta + g(u) = 0 \text{ in }Q \] with initial conditions \(u(0,x) = u_0 (x)\), \(u_t (0,x) =
Nandakumaran, A. K., George, R. K.
openaire   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Perturbations of Admissibility, Exact Controllability, Exact Observability and Regularity

open access: yes, 2016
This paper is concerned with the notions of admissibility, exact controllability, exact observability and regularity of linear systems in the Banach space setting. It is proved that admissible controllability, exact controllability, admissible observation, exact observability and regularity are invariant under some regular perturbations of the ...
Mei, Zhan-Dong, Peng, Ji-Gen
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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