Results 41 to 50 of about 55,282 (264)
Local time statistics and permeable barrier crossing: From Poisson to birth-death diffusion equations [PDF]
Physical Review ResearchBarrier crossing is a widespread phenomenon across natural and engineering systems. While abundant cross-disciplinary literature on the topic has emerged over the years, the stochastic underpinnings of the process have yet to be linked quantitatively to ...
T. Kay, L. Giuggioli
semanticscholar +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Quantifying the uncertainty in change points [PDF]
, 2011 Quantifying the uncertainty in the location and nature of change points in time series is important in a variety of applications. Many existing methods for estimation of the number and location of change points fail to capture fully or explicitly the ...
Aston, John A. D. +5 more
core +1 more source
Journal of Education, Health and Sport, 2015 Mikołajczyk Janusz, Byzdra Krzysztof, Piątek Mirosław, Kamrowska-Nowak Maria, Stępniak Robert. Analiza Wyników w Skokach Lekkoatletycznych Mężczyzn na Halowych Mistrzostwach Świata w Latach 1985-2006 = Analysis of Performance in Athletics Jumping Men on
Janusz Mikołajczyk +4 more
doaj +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Probability distribution theory, generalisations and applications of l-moments [PDF]
, 2001 In this thesis, we have studied L-moments and trimmed L-moments (TL-moments) which are both linear functions of order statistics. We have derived expressions for exact variances and covariances of sample L-moments and of sample TL-moments for any sample ...
Elamir, Elsayed Ali Habib +1 more
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Chaos communication performance : theory and computation [PDF]
, 2010 In this paper new and existing approaches are developed to compute the bit error rate for chaos-based communication systems. The multi-user coherent antipodal chaos shift keying system is studied and evaluated in its coherent form, in the sense of ...
Lawrance, Anthony J. +11 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source