Results 51 to 60 of about 178,657 (259)
Null controllability of one-dimensional parabolic equations by the flatness approach [PDF]
, 2015 We consider linear one-dimensional parabolic equations with space dependent coefficients that are only measurable and that may be degenerate or singular.Considering generalized Robin-Neumann boundary conditions at both extremities, we prove the null ...
Martin, Philippe +2 more
core +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Local Exact One-Sided Boundary Null Controllability of Entropy Solutions to a Class of Hyperbolic Systems of Balance Laws [PDF]
SIAM Journal of Control and Optimization, 2017 We consider nxn hyperbolic systems of balance laws in one-space dimension under the assumption that all negative (resp. positive) characteristics are linearly degenerate.
Tatsien Li, Lei Yu
semanticscholar +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Some controllability results for the N-Dimensional Navier-Stokes and Boussinesq systems with N-1 scalar controls [PDF]
, 2006 In this paper we deal with some controllability problems for systems of the Navier-Stokes and Boussinesq kind with distributed controls supported in small sets.
Fernández Cara, Enrique +3 more
core
Hardy inequality and Pohozaev identity for operators with boundary singularities: some applications [PDF]
, 2011 We consider the Schr\"{o}dinger operator $A_\l:=-\D -\l/|x|^2$, $\l\in \rr$, when the singularity is located on the boundary of a smooth domain $\Omega\subset \rr^N$, $N\geq 1$ The aim of this Note is two folded.
Bardos +15 more
core +5 more sources
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source
On exact controllability of linear time delay systems of neutral type [PDF]
, 2007 The problem of exact null controllability is considered for linear neutral type systems with distributed delay. A characterization of this problem is given. The minimal time of controllability is precised.
A. Bensoussan +11 more
core +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source