Results 71 to 80 of about 7,879,697 (288)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Purpose. Reveal the peculiarities of the formation of national varietal resources of grapes, considering current state of the market, needs of consumers, problems and prospects of the viticulture industry in Ukraine. Results.
С. І. Мельник +4 more
doaj +1 more source
Examination of the psychometric properties of the children’s loneliness scale for students with and without special needs in inclusive classrooms* [PDF]
Early detection of loneliness in children, especially children with special needs who are at greater risk for loneliness, is crucial for planning appropriate interventions.
Küçüker, Sevgi, Tekinarslan, I.C.
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Розглянуто питання розроблення технологій клонального мікророзмноження на безвірусній основі цінних і перспективних гірких сортів хмелю та вивчення морфогенетичних потенціалів різних клітин, тканин та органів хмелю в умовах культури in vitro.
А. О. Глибовець +2 more
doaj +1 more source
Academic Ethics: What has Morality, Culture and Administration got to do with its Measurement? [PDF]
While there is no dearth of studies on ethical issues, the specific subject of examination misconduct has attracted fewer studies, especially in Africa. This study is an ongoing exploratory attempt to develop a measure of examination misconduct.
Gbadamosi, Gbolahan
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

