Results 71 to 80 of about 78,396 (269)

The reinvestigation of Hoffman's/Robberg cave - the artefactual and shellfish assemblages, 2007

open access: yes, 2009
Includes abstract.Includes bibliographical references (leaves 150-159).This thesis documents the re-investigation of Hoffman's/Robberg Cave, a little known site located on the Robberg Peninsula near Plettenberg Bay on the southern Cape coast of South ...
Kyriacou, Katharine
core  

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

open access: yesAdvanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen   +8 more
wiley   +1 more source

Tudor and early Stuart vessel glass: an archaeological study of forms and patterns of consumption in England, 1500 to 1640 [PDF]

open access: yes, 1999
The aims of this thesis are twofold. The first is concerned with the establishment of a typology for vessel glass in England between 1500 and 1640. There has been no morphological classification for glass of this period and one is constructed in this ...
Willmott, Hugh Benedict, Willmott, H.B.
core  

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

open access: yesAdvanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong   +12 more
wiley   +1 more source

Gender analysis of 1990-1992 excavations of burials in Pokrovka, Russia

open access: yes, 2011
The following work examines in detail the data recovered from the 1990-1992 burial excavations at the site of Pokrovka in southern Russia dating from the second half of the second millennium B.C. to fourteen century A.D.
Lorge, Jennifer Rose
core  

Excavations at Saqqara

open access: yes, 1909
With sections by Herbert Thompson and W.
Quibell, James Edward
core   +1 more source

NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice

open access: yesAdvanced Science, EarlyView.
In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu   +15 more
wiley   +1 more source

THE HISTORICAL AND ARCHEOLOGICAL EXPLORATION OF THE NORTH-WESTERN CAUCASUS IN THE FIRST HALF OF THE XIX CENTURY (ACCORDING TO THE MATERIALS OF KRASNODAR STATE ARCHIVES)

open access: yesГуманитарные и юридические исследования, 2021
The article studies the features of archeological antiquities exploration carried out in the North-Western Caucasus in the first half of the XIX century.
Y. . Klychnikov
doaj  

Trinkets and Charms: the use, meaning and significance of later medieval and early post-medieval dress accessories [PDF]

open access: yes, 2010
This is a thematic study of dress accessories of late medieval to early post-medieval date from two regions of mainland Britain. It is an investigation of everyday objects which aims to re-engage the material world with past individuals.
STANDLEY, ELEANOR,ROSE
core  

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu   +11 more
wiley   +1 more source

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