Results 101 to 110 of about 1,605,966 (319)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Random walk, excess smoothness or excess sensitivity? Evidence from literature and an application for Turkish economy

open access: yes
This paper observes the Turkish household’ consumption data to see whether it follows random walk or not. The quarterly data covers the period from 1987:1 to 2003:4.
Bilgili, Faik
core   +1 more source

Ekstatyczne eksplozje. Wajda, afekty i reparacja

open access: yesTeksty Drugie, 2018
Andrzej Wajda’s films are based on visual excess. His method consists of a loose stringing together of contrasting images, which brings to mind Sergei Eisenstein’s notion of pathos. Both Wajda and Eisenstein conceive of affects as structures that work on
Sebastian Jagielski
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Excess wage computation

open access: yes, 2012
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on June 12, 2015)."UI PUB 217

core  

On excessive sweating [PDF]

open access: yesDublin Quarterly Journal of Medical Science
n ...
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Excess wage computation

open access: yes, 2011
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on June 12, 2015)."UI PUB 217

core  

CRIMINAL LAW CONCEPTUALIZATION OF THE CATEGORY “OFFICIAL AUTHORITY” AS A NECESSARY PREREQUISITE FOR A UNIFORM DELINEATION OF THE CRIMES PROVIDED FOR BY ARTICLES 285 AND 286 OF THE CRIMINAL CODE OF THE RUSSIAN FEDERATION

open access: yesПравовое государство: теория и практика
The relevance of the problems of this article is due to the need to improve law enforcement practice in the field of qualification of crimes under Articles 285 and 286 of the Criminal Code of the Russian Federation.
POPOVA Evgenia Mikhailovna
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Home - About - Disclaimer - Privacy