Results 101 to 110 of about 1,258,948 (264)
Combinatorial excess intersection
Journal of Symbolic Computation, 2015 We provide formulas and algorithms for computing the excess numbers of certain ideals. The solution for monomial ideals is given by the mixed volumes of certain polytopes. These results enable us to design specific homotopies for numerical algebraic geometry.
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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Verdant Surfaces and Ambiguous Vividity: Ebony G. Patterson at CAMSTL
Miranda: Revue Pluridisciplinaire du Monde Anglophone, 2021 Jay Buchanan
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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Ekstatyczne eksplozje. Wajda, afekty i reparacja
Teksty Drugie, 2018 Andrzej Wajda’s films are based on visual excess. His method consists of a loose stringing together of contrasting images, which brings to mind Sergei Eisenstein’s notion of pathos. Both Wajda and Eisenstein conceive of affects as structures that work on
Sebastian Jagielski
doaj
Excessive Anonymous/The Anonymity of Excess
Iowa Journal of Cultural Studies, 1994 Coyne, Amanda, Vaingurt, Julia
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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