Results 141 to 150 of about 1,605,966 (319)

Taxation and Excess Burden: A Life-Cycle Perspective [PDF]

open access: yes
A lifetime perspective is appropriate in assessing the welfare implications of government tax policies. Although a number of attempts have been made to ex- amine the excess burden of taxation in life-cycle models, these have tended to ignore the role of ...
Harvey S. Rosen, E. John Driffill
core  

Excessive Anonymous/The Anonymity of Excess

open access: yesIowa Journal of Cultural Studies, 1994
Coyne, Amanda, Vaingurt, Julia
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The Theory of Excess Burden and Optimal Taxation [PDF]

open access: yes
The purpose of this paper is to present the chronological development ofthe concept of excess burden and the related study of optimal tax theory. A main objective of this exercise is to uncover the interrelationships among various apparently distinct ...
Alan J. Auerbach
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Will the Real Excess Burden Please Stand Up? (Or, Seven Measures in Search of a Concept) [PDF]

open access: yes
It is well understood that a tax which distorts relative prices generates a welfare cost or "excess burden" in addition to any associated transfer of resources, but there remains considerable controversy and confusion with respect to procedures for ...
Harvey S. Rosen, Alan J. Auerbach
core  

Desbordes. Vida, política y estéticas del exceso en Osvaldo Lamborghini y Diamela Eltit

open access: yesPerífrasis. Revista de Literatura, Teoría y Crítica, 2016
Este artículo se propone analizar los modos como dos ficciones latinoamericanas contemporáneas, Sebregondi retrocede (1973) de Osvaldo Lamborghini e Impuesto a la carne (2010) de Diamela Eltit, problematizan las relaciones entre los saberes sobre los ...
María Cecilia Sánchez Idiart
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

A Note on the Excess Entry Theorem in Spatial Models with Elastic Demand [PDF]

open access: yes
This paper revisits the excess entry theorem in spatial models à la Vickrey (1964) and Salop (1979) while relaxing the assumption of inelastic demand. Using a demand function with a constant demand elasticity, we show that the number of firms that enter ...
Yiquan Gu, Tobias Wenzel
core  

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