Results 131 to 140 of about 1,605,966 (319)

Combinatorial excess intersection

open access: yesJournal of Symbolic Computation, 2015
We provide formulas and algorithms for computing the excess numbers of certain ideals. The solution for monomial ideals is given by the mixed volumes of certain polytopes. These results enable us to design specific homotopies for numerical algebraic geometry.
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

New insights into the fermentation switch: Dynamic transcriptional response to anaerobicity and glucose-excess-0

open access: yes, 2011
Copyright information:Taken from "New insights into the fermentation switch: Dynamic transcriptional response to anaerobicity and glucose-excess"http://www.biomedcentral.com/1471-2164/9/100BMC Genomics 2008;9():100-100.Published online 27 Feb 2008PMCID ...
Joost van den Brink (90366)   +3 more
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Direct perturbations of aggregate excess demand [PDF]

open access: yes
We establish that an exchange economy, i.e., preferences and endowments, that generates a giiven aggregate excess demand (AED) function is close to the economy generating the AED obtained by an arbitrary perturbation of the original one.Arrow-Debreu ...
Sami Dakhlia   +2 more
core  

Excess body fat in obese and normal weight subjects

open access: yes, 2012
Excess body adiposity, especially abdominal obesity and ectopic fat accumulation, are key risk factors in the development of a number of chronic diseases.
Taylor-Robinson, S.D.   +3 more
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

The Excess Smoothness of Consumption: Identification and Interpretation [PDF]

open access: yes
The paper investigates the implications of the omitted information problem -- that is, the econometric problem which arises because an econometrician cannot explicitly include the complete set of variables potentially used by agents -- in the context of ...
Marjorie A. Flavin
core  

Antidepressant excess [PDF]

open access: yesJournal of the Royal Society of Medicine, 2016
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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