Results 31 to 40 of about 1,605,966 (319)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
, 2015 <p>This is the first working prototype version of Excess.</p ...
xs-admin, xkp
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Witchfinding in General and the Censors [PDF]
, 2017 This article examines why it took 33 years before Mark of the Devil (1970) could be distributed in its complete form in the UK. It shows that when the film was first submitted to the British Board of Film Censors in 1970 the cuts required were so ...
Petley, J
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Hard Touch: Gore Capitalism and Teresa Margolles’s Soft Interventions
Hart, 2020 This text approaches Teresa Margolles’s textile works through the lens of gore capitalism, a concept theorized in Sayak Valencia’s important 2018 book.
Julia
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Film-PhilosophyThis article argues that Antonin Artaud's theory of the theatre of cruelty, elaborated in The Theatre and Its Double, and the procedures of Sergei Parajanov's The Colour of Pomegranates (1969) bear a crucial affinity.
Alexander Dickow
doaj +1 more source
British Journal of General Practice, 2018 In this month’s BJGP we feature some major themes in contemporary health care — the national consultation on organ donation, the rising tide of antibiotic resistance, child health, including childhood obesity, and the roles of other professionals, working alongside doctors, in general practice.
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source