Results 51 to 60 of about 1,272,486 (269)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Jean Viviès. George Cheyne, médecin de son siècle, 1672-1743, Malaise dans la civilisation anglaise.

open access: yesMiranda: Revue Pluridisciplinaire du Monde Anglophone, 2023
Hélène Dachez
doaj   +1 more source

Intermittent Resistance Exercise: Evolution from the Steady State

open access: yesCentral European Journal of Sport Sciences and Medicine, 2014
Oxygen uptake measurements are without question useful and a staple measurement for the estimation of exercise energy costs. However, steady state models cannot be used to successfully model intermittent resistance exercise energy costs.
Christopher B. Scott
doaj  

La Vie d’Adèle : un roman d’apprentissage mélodramatique

open access: yesMise au Point, 2016
This article demonstrates with which cinematographic processes, the film Blue is The Warmest Color shapes an aesthetic of excess that depicts emotions on the characters’ bodies but also on the spectators’bodies.
Sabrina Bouarour
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Calculating of asymmetry and excess coefficients for chromatographic peaks by using chebyshev – hermite functions and gram – charlier series

open access: yesВестник Самарского государственного технического университета. Серия: Технические науки, 2020
The paper deals with the development of an algorithm for computation of excess and asymmetry coefficients for chromatographic peak, given by Gram-Charlier series. Investigation of possibility using direct transformation of coefficients of signal decoding
Rauhat T. Sayfullin, Andrey V. Bochkarev
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The excess

open access: yesEikasía
The following brief notes, devoted to the experience we call «excess», aim to account for the phenomenon of the «own body», as opposed to the body-thing (Körper).
Pelayo Pérez García, Samuele Arrigoni
doaj   +1 more source

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