Results 71 to 80 of about 40,746 (261)

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Theoretical Analysis of Drilling Unloading and Pile-Side Soil Pressure Recovery of Nonsqueezing Pipe Piles Installed in K0-Consolidated Soils

open access: yesBuildings
Drilling with prestressed concrete (DPC) pipe pile is a nonsqueezing pile sinking technology, employing drilling, simultaneous pile sinking, a pipe pile protection wall, and pile side grouting.
Bo Li   +7 more
doaj   +1 more source

Consolidated and Undrained Ring Shear Tests on the Sliding Surface of the Hsien-du-shan Landslide in Taiwan

open access: yesGeofluids, 2018
A new consolidated undrained ring shear test capable of measuring the pore pressures is presented to investigate the initiation mechanism of the Hsien-du-shan rock avalanche, triggered by Typhoon Morakot, in southern Taiwan.
Hung-Ming Lin   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Excess Pore Pressure Migration Analysis Due to High Embankment Construction – Case Study East Kalimantan

open access: yesJournal of the Civil Engineering Forum
A 42-inch pipeline traverses a predominantly flat right-of-way (ROW), running from south to north in East Kalimantan. Adjacent to the ROW, a coal mine concession was located on the western side, while the Mahakam River lies a further 3 km to the east. A
Edwin Lie   +2 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Stability Analysis of Coastal Sheet Pile Wall Considering Soil Weakening Induced by Earthquake Loading

open access: yesJournal of Marine Science and Engineering
A sheet pile wall is a widely used retaining structure in coastal and riverbank areas. In liquefiable soils, seismic activity can generate excess pore pressure, which not only increases the load on the sheet pile wall but also reduces the soil strength ...
Shuai Ning, Qiang Ma, Yuan Cao
doaj   +1 more source

Field tests on excess pore pressure and soil pressure of pile-soil interface for a single pile during pile-sinking in clay

open access: yesYantu gongcheng xuebao, 2019
Stress change of pile-soil interface for jacked-in piles during pile-sinking in clay is a topic of concern in the geotechnical engineering. A full-scale jacked-in pile is penetrated into the clay in Dongying city of China and studied by monitoring the ...
WANG Yong-hong 1,2, ZHANG Ming-yi 1,2, LIU Jun-wei 1,2, BAI Xiao-yu 1,2, YANG Su-chun 1, SANG Song-kui 1, YAN Nan 3
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

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