Results 41 to 50 of about 170,194 (350)

Field Test Investigation of the Pile Jacking Performance for Prefabricated Square Rigid-Drainage Piles in Saturated Silt Sandy Soils

open access: yesAdvances in Civil Engineering, 2019
The rigid-drainage pile, designed to accelerate the dissipation of excess pore water pressure around the pile, is a new type of pile that combines the bearing capacity of ordinary rigid piles and the draining capacity of gravel piles.
Xiangying Wang
doaj   +1 more source

Laboratory Tests on Open-Close Pile Jacking and Load Bearing Characteristics in Saturated Clay Soil

open access: yesAdvances in Civil Engineering, 2022
The stress characteristics of the pile-soil interface have an important influence on the effect and long-term bearing capacity of jacked piles. In order to obtain the stress characteristics of the pile-soil interface of the jacked pile in clay, the ...
Qiang Song   +10 more
doaj   +1 more source

Dissipated energy in undrained cyclic triaxial tests [PDF]

open access: yes, 2015
Energy-based methods are an emerging tool for the evaluation of liquefaction potential. These methods relate excess pore water pressure build-up to seismic energy dissipated per unit volume.
Azeiteiro, RJN   +3 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Experimental Study on the Uplift Correction of Raft Foundations in Saturated Silty Clay

open access: yesBuildings
Although grouting technology has been widely applied for lifting and rectifying tilted structures, theoretical research remains underdeveloped and lags behind the practical demands of engineering applications. In this study, a self-developed experimental
Tengyue Cui, Yingguang Shi, Feng Huang
doaj   +1 more source

The effect of undrained heating on a fluid-saturated hardened cement paste [PDF]

open access: yes, 2008
The effect of undrained heating on volume change and induced pore pressure increase is an important point to properly understand the behaviour and evaluate the integrity of an oil well cement sheath submitted to rapid temperature changes.
Ghabezloo, Siavash   +2 more
core   +5 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The effect of pore water pressure distribution induced by rainfall infiltration on the failure of unsaturated soil slopes [PDF]

open access: yesE3S Web of Conferences
Numerical analysis was performed based on the Material Point Method (MPM) to analyze the failure mechanisms of unsaturated slopes due to rainfall infiltration. A coupled hydro-mechanical finite element model was applied to solve the rainfall infiltration
Lee Kwangwoo   +2 more
doaj   +1 more source

Using stone column as a suitable liquefaction remediation in Persian Gulf coast. [PDF]

open access: yes, 2010
This research investigates behavior of gravel drain piles under high-level earthquake loading beneath the structures foundation. To achieve this purpose one of the waste water septic tank project in north of Persian Gulf in Hormoz Island was selected ...
Kim Huat, Bujang   +4 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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