Results 61 to 70 of about 36,521 (298)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Understanding the microscopic moisture migration in pore space using DEM simulation

Journal of Rock Mechanics and Geotechnical Engineering, 2015
The deformation of soil skeleton and migration of pore fluid are the major factors relevant to the triggering of and damages by liquefaction. The influence of pore fluid migration during earthquake has been demonstrated from recent model experiments and ...
Yuan Guo, Xiong (Bill) Yu
doaj   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Study of the Pore Water Pressure Development Characteristics of PHC Pipe Piles in Soft Soil Foundations

Buildings
When constructing hollow prestressed high-strength concrete (PHC) pipe piles in soft soil foundations, the generation and dissipation of pore water pressure can induce negative friction on the pile.
Zhaolin Jia, Han Wu, Shuaiqi He, Qixiang Zhao, Xiaoxu Zhang   +4 more
doaj   +1 more source

A 57‐Year‐Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This report presents a case of behavioral variant frontotemporal dementia caused by mutations in the MATR3 and NOS3 genes, aiming to analyze its clinical manifestations and genetic characteristics. For a case presenting with personality changes and gait abnormalities as the initial symptoms, this study conducted a comprehensive analysis of its
Feifei Lin, Saie Huang
wiley   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J. S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source

In-situ tests on pore-water pressure response and consolidation mechanism of surface sediments in tidal flat of Yellow River Delta under tide and wave loading

Yantu gongcheng xuebao
In order to study the pore pressure response and consolidation mechanism of the surface sediments in the tidal flat of the Yellow River Delta under the action of wave and tide loading, the fluid sediments imitating the rapidly deposited seabed silty ...
ZHANG Jianmin 1, 2, SHAN Hongxian 3, WANG Zhenqiang 1, 2, WANG Zhicai 1, 2, WANG Jinjin 1, 2
doaj   +1 more source

Field tests on response of excess pore water pressures of liquefaction resistant rigid-drainage pile

Yantu gongcheng xuebao, 2017
The liquefaction resistant rigid-drainage pile is a new type of pile which can be used in geotechnical earthquake engineering. The pile combines the bearing capacity of rigid pile and the drain-ability of gravel pile.
WANG Xiang-ying 1, 2, LIU Han-long 1, 2, 3, JIANG Qiang 1, 2, 4, CHEN Yu-min 1, 2
doaj   +1 more source

Degree of consolidation - peaked initial excess pore water pressure distributions

, 2011
The solution to Terzaghi's one-dimensional consolidation equation can be freely found in literature for two different cases of initial excess pore water pressure varying with depth; linear or uniform.
Lovisa, J., Read, W.W, Sivakugan, N.
core  

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

Advanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi, Pasquale Guglielmi, Gianfranco Palumbo, Giuseppe Carbone   +3 more
wiley   +1 more source