Results 41 to 50 of about 36,521 (298)

Field Test Investigation of the Pile Jacking Performance for Prefabricated Square Rigid-Drainage Piles in Saturated Silt Sandy Soils

Advances in Civil Engineering, 2019
The rigid-drainage pile, designed to accelerate the dissipation of excess pore water pressure around the pile, is a new type of pile that combines the bearing capacity of ordinary rigid piles and the draining capacity of gravel piles.
Xiangying Wang
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Experimental Study on the Uplift Correction of Raft Foundations in Saturated Silty Clay

Buildings
Although grouting technology has been widely applied for lifting and rectifying tilted structures, theoretical research remains underdeveloped and lags behind the practical demands of engineering applications. In this study, a self-developed experimental
Tengyue Cui, Yingguang Shi, Feng Huang
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Long-term settlement of tunnel caused by shield tunneling in peaty soil

Yantu gongcheng xuebao, 2017
In order to study the long-term settlement of tunnel caused by shield tunneling in peaty soil, the surrounding soil of tunnel is regarded as continuum, homogeneous and isotropic saturated viscoelastic medium.
WANG Zhi-liang , QU Jia-an , SHEN Lin-fang , XU Ze-min , DING Zu-de
doaj   +1 more source

Excess pore water pressure generation in fine granular materials under cyclic loading -A laboratory study

, 2021
Excess pore water pressure can be generated in subgrades of both railway and pavement sub-structures under cyclic loading caused by heavy traffic. When saturated subgrades are subjected to cyclic loading, excess pore water pressures accumulate over time ...
Do, Tan Manh
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Comparison Study on the Residual Excess Pore Water Pressure Observed in seabed [PDF]

Journal of Korean navigation and port research, 2013
The interaction among wave, seabed and marine structure is an important issue in coastal engineering as well as geotechnical engineering. Understanding variations of stresses and pore water pressures generated in seabed induced by waves is important for civil engineers who have to design the foundation for various marine structures and verify the ...
openaire   +1 more source

The effect of pore water pressure distribution induced by rainfall infiltration on the failure of unsaturated soil slopes [PDF]

E3S Web of Conferences
Numerical analysis was performed based on the Material Point Method (MPM) to analyze the failure mechanisms of unsaturated slopes due to rainfall infiltration. A coupled hydro-mechanical finite element model was applied to solve the rainfall infiltration
Lee Kwangwoo, Ferrari Alessio, Laloui Lyesse   +2 more
doaj   +1 more source