Results 51 to 60 of about 170,194 (350)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Shuiwen dizhi gongcheng dizhi, 2022 The Daguangbao landslide is the largest co-seismic landslide with a volume of approximately 12×108 m3, which triggered by the Wenchuan earthquake (Ms 8.0) occurred on May 12, 2008.
Xingxing SHI +4 more
doaj +1 more source
Catalogue of analytical solutions for consolidation of unsaturated soils subjected to various initial conditions and time-dependent loadings [PDF]
, 2016 University of Technology Sydney. Faculty of Engineering and Information Technology.Soil consolidation has been a primary geotechnical interest for decades.
Ho, Huu Liem
core
Advanced SBAS-DInSAR technique for controlling large civil infrastructures: an application to the Genzano di Lucania dam [PDF]
, 2018 Monitoring surface deformation on dams is commonly carried out by in situ geodetic surveying, which is time consuming and characterized by some limitations in space coverage and frequency.
Corsetti, Marco +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Open GeosciencesTo study the liquefaction problem of the dam foundation of an ultra-deep overburden in the strong earthquake area, a large-scale shaking table model test is carried out based on a 500 m rockfill dam project on an ultra-deep overburden.
Xing Yang +4 more
doaj +1 more source
Understanding the microscopic moisture migration in pore space using DEM simulation
Journal of Rock Mechanics and Geotechnical Engineering, 2015 The deformation of soil skeleton and migration of pore fluid are the major factors relevant to the triggering of and damages by liquefaction. The influence of pore fluid migration during earthquake has been demonstrated from recent model experiments and ...
Yuan Guo, Xiong (Bill) Yu
doaj +1 more source
Analysing consolidation data to optimise elastic visco-plastic model parameters for soft clay [PDF]
, 2015 University of Technology Sydney. Faculty of Engineering and Information Technology.Analysing the behaviour of soft soils under embankments is a significant challenging task for geotechnical engineers.
Le, TM
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