Results 51 to 60 of about 488,251 (257)

Assessing two methods for estimating excess mortality of chronic diseases from aggregated data

BMC Research Notes, 2020
Objective To assess the numerical properties of two recently published estimation techniques for excess mortality based on aggregated data about diabetes in Germany.
Ralph Brinks, Thaddäus Tönnies, Annika Hoyer   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Conductive BaCuTeF thin films for transparent contacts for semiconductor electronics [PDF]

Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2008
Сhemical composition, structural and electrical properties of the BaCuTeF thin films were investigated. Dependence of the copper excess on the deposition parameters was studied. Excess of copper improves the electrical properties of the films by means of
Hotra Z. Y., Tate J., Kykyneshi R.,, Zakutayev A. A., Rakobovchuk L.M.   +4 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Cold Dust Properties and Submillimeter Excess in 33 Nearby Spiral Galaxies

The Astrophysical Journal Supplement Series
The origin of submillimeter excess in galaxies remains unclear. We analyze cold dust properties of 33 nearby spiral galaxies, identify a possible 850 μ m excess, and explore its environments.
Zhengxue Chang, Jianjun Zhou, Isabella Lamperti, Amélie Saintonge, Xiangyun Zeng, Shumin Wang, Jarken Esimbek, Ruimin Shi, Jianjie Qiu, Na Zhao, Yuxin He, Qiang Li, Linlin Li, Long Huang, Hailiang Shen, Xiaona Liu   +15 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Exploration of the intermolecular interactions in polyethylene glycol 400 + alkyl methacrylate mixtures at ambient temperatures by means of thermophysical and spectroscopic methods

Chemical Thermodynamics and Thermal Analysis
Thermophysical and spectral analysis for binary systems comprising polyethylene glycol 400 and alkyl methacrylate have been carried in this study with an objective to understand the molecular interactions therein.
Anil Kumar Nain, Nidhi, Neha Chaudhary
doaj   +1 more source

Properties of Methanol-Water Mixtures in a Coarse-Grained Model

Acta Chimica Slovenica, 2015
Methanol and water rank among the most important liquids in modern world due to their versatile use. As water, methanol and their mixture exhibit numerous anomalous properties, their description is challenging.
Matej Huš, Gašper Žakelj, Tomaž Urbič   +2 more
doaj   +1 more source