Results 71 to 80 of about 783,699 (277)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Experiences Using MEMS Accelerometers on Railway Bearers at Switches and Crossings to Obtain Displacement—Awkward Situations

Infrastructures
A sleeper, or more generally a “bearer”, moves vertically under a passing train load. The extent of this motion depends on the static and dynamic load of the train, the train speed, and the support conditions at the bearer and its neighbours.
Jou-Yi Shih, Paul Weston, Mani Entezami, Clive Roberts, Mark O’Callaghan   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Electronic mechanical braking system executive mechanism design, calculation, and modeling based on dynamic control

Frontiers in Mechanical Engineering
Introduction: As science and technology develop, automobiles are moving toward intelligence and electrification and need better braking systems.Methods: To improve the braking system’s response speed and braking effect, a longitudinal dynamics control ...
Xinping Wu, Rongnian He, Han Ge, Mengyu Chen   +3 more
doaj   +1 more source

Increased rate of acceleration on Pine Island Glacier strongly coupled to changes in gravitational driving stress [PDF]

, 2009
Pine Island Glacier, Antarctica, has been undergoing several related changes for at least two decades; these include acceleration, thinning and grounding line retreat.
Scott, J. B. T., Vaughan, D G, Bingham, R. G., R. G. Bingham, Pritchard, H.D., Vaughan, D. G., Bingham, R.G., Pritchard, Hamish D., Scott, J.B.T., Smith, A. M., Vaughan, D.G., Pritchard, H. D., J. B. T. Scott, Gudmundsson, G H, Smith, A M, Pritchard, H D, Smith, A.M., Gudmundsson, G.H., D. G. Vaughan, Vaughan, David G., G. H. Gudmundsson, Scott, J B T, H. D. Pritchard, Bingham, R G, Gudmundsson, G. H., Gudmundsson, Hilmar, A. M. Smith, Bingham, Robert G.   +27 more
core   +2 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Speed excess and total acceleration: a kinematical approach to entanglement

Physica Scripta
Abstract The total variance of a spin state is defined as the average of the variances of spin projection measurements along three orthogonal axes. We show that this quantity also gives the squared rotational speed of the state in projective space, averaged over all rotation axes.
C Chryssomalakos, A G Flores-Delgado, E Guzmán-González, L Hanotel, E Serrano-Ensástiga   +4 more
openaire   +3 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Excessive menstrual bleeding.

, 1991
One out of every 6 women have problems with heavy menstrual bleeding. This is a major cause of anaemia and poor health. Often the condition is treated by hysterectomy.
HRB Excessive Menstrual Bleeding Research Unit
core